IsoMeranzin

Base Information

• Chemical Name: IsoMeranzin
• CAS No.: 1088-17-1
• Molecular Formula: C₁₅H₁₆O₄
• Molecular Weight: 260.29
• Mol file: 1088-17-1.mol

Synonyms:Coumarin,7-methoxy-8-(3-methyl-2-oxobutyl)- (7CI,8CI); Isoaurapten; Isoauraptene;Isomerancin; Isomerazin

Chemical Property of IsoMeranzin

Chemical Property:

• Melting Point: 66 °C
• Boiling Point: 423.4±45.0 °C(Predicted)
• Density: 1.178±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

Isomeranzin 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of IsoMeranzin

There total 10 articles about IsoMeranzin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

erythro-dihydromurrangatin (51552-09-1,120787-71-5,121960-63-2) → isomeranzin (1088-17-1)

Guidance literature:

With sulfuric acid; for 1.5h; Heating;

DOI:10.1016/S0040-4039(00)82292-3

Reference yield: 31.0%

acetic anhydride (108-24-7) + 7-methoxy-8-((3,3-dimethyloxiran-2-yl)methyl)-2H-chromen-2-one (489-53-2) → Auraptenol acetate (93525-00-9) + isomeranzin (1088-17-1) + 7-Methoxy-8-(2'-chloro-3'-hydroxy-3'-methylbutyl)coumarin (93524-99-3)

Guidance literature:

With pyridine hydrochloride; Yield given. Multistep reaction;

Reference yield: 31.0%

7-methoxy-8-((3,3-dimethyloxiran-2-yl)methyl)-2H-chromen-2-one (489-53-2) → Auraptenol acetate (93525-00-9) + isomeranzin (1088-17-1) + 7-Methoxy-8-(2'-chloro-3'-hydroxy-3'-methylbutyl)coumarin (93524-99-3)

Guidance literature:

With pyridine hydrochloride; In pyridine; for 3h; Product distribution; Heating;

upstream raw materials:

Merancin

acetic anhydride

7-methoxy-8-((3,3-dimethyloxiran-2-yl)methyl)-2H-chromen-2-one

erythro-dihydromurrangatin

Refernces

• 1、 Nikonov,Saidkhodzhaev. "-". . . Retrieved 1971.
• 2、 Barik, Bikash R.,Dey, Ashesh K.,Das, Probhash C.,Kundu, Amit B.,Chatterjee, Asima. "Molecular Rearrangement of Osthol Epoxide with Pyridinium Chloride and Trifluoracetic acid". . p. 223 - 226. Retrieved 2007/10/02.