(Z)-methyl 3-bromo-4-(methoxy(phenyl)methyleneamino)benzoate

Base Information

• Chemical Name: (Z)-methyl 3-bromo-4-(methoxy(phenyl)methyleneamino)benzoate
• CAS No.: 1402939-11-0
• Molecular Formula: C₁₆H₁₄BrNO₃
• Molecular Weight: 348.196
• Mol file: 1402939-11-0.mol

Synonyms:(Z)-methyl 3-bromo-4-(methoxy(phenyl)methyleneamino)benzoate

Chemical Property of (Z)-methyl 3-bromo-4-(methoxy(phenyl)methyleneamino)benzoate

Chemical Property:

Purity/Quality:

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Technology Process of (Z)-methyl 3-bromo-4-(methoxy(phenyl)methyleneamino)benzoate

There total 1 articles about (Z)-methyl 3-bromo-4-(methoxy(phenyl)methyleneamino)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

methyl 4-amino-3-bromobenzoate (106896-49-5) + orthobenzoic acid trimethyl ester (707-07-3) → (Z)-methyl 3-bromo-4-(methoxy(phenyl)methyleneamino)benzoate (1402939-11-0)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 3h; Inert atmosphere; Reflux;

DOI:10.1021/jo301805d

Reference yield: 76.0%

(Z)-methyl 3-bromo-4-(methoxy(phenyl)methyleneamino)benzoate (1402939-11-0) + p-toluidine (106-49-0,12221-03-3) → methyl 4-oxo-2-phenyl-3-p-tolyl-3,4-dihydroquinazoline-6-carboxylate (1402939-25-6)

Guidance literature:

With carbon monoxide; palladium diacetate; caesium carbonate; catacxium A; In toluene; at 85 ℃; for 18h; Inert atmosphere; Microwave irradiation;

DOI:10.1021/jo301805d

upstream raw materials:

methyl 4-amino-3-bromobenzoate

orthobenzoic acid trimethyl ester

Downstream raw materials:

methyl 4-oxo-2-phenyl-3-p-tolyl-3,4-dihydroquinazoline-6-carboxylate