C₂₆H₂₆O₇

Base Information

• Chemical Name: C₂₆H₂₆O₇
• CAS No.: 253590-03-3
• Molecular Formula: C₂₆H₂₆O₇
• Molecular Weight: 450.488
• Mol file: 253590-03-3.mol

Synonyms:C₂₆H₂₆O₇

Chemical Property of C₂₆H₂₆O₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₆O₇

There total 13 articles about C₂₆H₂₆O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

C26H25BrO7 (253590-01-1) → C26H26O7 (253590-03-3)

Guidance literature:

With water; ammonium chloride; zinc; In tetrahydrofuran; Heating;

DOI:10.1039/a905631i

Reference yield:

benzoyl chloride (98-88-4) → C26H26O7 (253590-03-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 90 percent / DMAP; pyridine

2: 91 percent / MCPBA / CH₂Cl₂ / 20 °C

3: BF₃*OEt₂ / toluene / -20 °C

4: HF / acetonitrile; tetrahydrofuran / 30 °C

5: 52 percent / DMAP; pyridine

6: 77 percent / Zn; NH₄Cl; H₂O / tetrahydrofuran / Heating

With pyridine; dmap; boron trifluoride diethyl etherate; hydrogen fluoride; water; ammonium chloride; 3-chloro-benzenecarboperoxoic acid; zinc; In tetrahydrofuran; dichloromethane; toluene; acetonitrile; 1: Acylation / 2: Epoxidation / 3: Ring cleavage / 4: Desilylation / 5: Acylation / 6: Ring cleavage;

DOI:10.1039/a905631i

Reference yield:

(+)-(1R,4S,4aR,5S,8aS)-5-tert-Butyldimethylsilyloxy-1,4,4a,6,7,8-hexahydro-endo-1,4-methanonaphthalen-8(5H)-one (194796-30-0) → C26H26O7 (253590-03-3)

Guidance literature:

Multi-step reaction with 12 steps

1: 89 percent / NaH / tetrahydrofuran / 20 °C

2: 82 percent / O₂; KF; (EtO)3P / dimethylsulfoxide

3: NaBH₄ / methanol; tetrahydrofuran / -15 °C

4: NBS / CH₂Cl₂ / -15 °C

5: 84 percent / POCl₃; pyridine / 50 °C

6: DIBAL-H / toluene / -78 °C

7: 90 percent / DMAP; pyridine

8: 91 percent / MCPBA / CH₂Cl₂ / 20 °C

9: BF₃*OEt₂ / toluene / -20 °C

10: HF / acetonitrile; tetrahydrofuran / 30 °C

11: 52 percent / DMAP; pyridine

12: 77 percent / Zn; NH₄Cl; H₂O / tetrahydrofuran / Heating

With pyridine; dmap; potassium fluoride; sodium tetrahydroborate; N-Bromosuccinimide; boron trifluoride diethyl etherate; hydrogen fluoride; water; oxygen; sodium hydride; diisobutylaluminium hydride; ammonium chloride; 3-chloro-benzenecarboperoxoic acid; zinc; triethyl phosphite; trichlorophosphate; In tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide; toluene; acetonitrile; 1: Condensation / 2: Oxidation / 3: Reduction / 4: Bromination / 5: Dehydration / 6: Reduction / 7: Acylation / 8: Epoxidation / 9: Ring cleavage / 10: Desilylation / 11: Acylation / 12: Ring cleavage;

DOI:10.1039/a905631i

upstream raw materials:

C₂₆H₂₅BrO₇

benzoyl chloride

(+)-(1R,4S,4aR,5S,8aS)-5-tert-Butyldimethylsilyloxy-1,4,4a,6,7,8-hexahydro-endo-1,4-methanonaphthalen-8(5H)-one

C₁₈H₂₉BrO₃Si