6,8-dimethoxy-1-(3-trifluoromethoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid (4-acetylphenyl)amide

Base Information

Chemical Name:6,8-dimethoxy-1-(3-trifluoromethoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid (4-acetylphenyl)amide
CAS No.:848900-75-4
Molecular Formula:C₂₇H₂₅F₃N₂O₅
Molecular Weight:514.501
Hs Code.:

Synonyms:6,8-dimethoxy-1-(3-trifluoromethoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid (4-acetylphenyl)amide

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Chemical Property of 6,8-dimethoxy-1-(3-trifluoromethoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid (4-acetylphenyl)amide

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Technology Process of 6,8-dimethoxy-1-(3-trifluoromethoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid (4-acetylphenyl)amide

There total 2 articles about 6,8-dimethoxy-1-(3-trifluoromethoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid (4-acetylphenyl)amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₈H₁₈F₃NO₃

: 49647-20-3
4-acetylphenyl isocyanate

: 848900-75-4
6,8-dimethoxy-1-(3-trifluoromethoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid (4-acetylphenyl)amide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 4h;

Reference yield:

: C₁₈H₁₈F₃NO₃

: 32315-10-9
bis(trichloromethyl) carbonate

: 99-92-3
p-aminobenzophenone

: 848900-75-4
6,8-dimethoxy-1-(3-trifluoromethoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid (4-acetylphenyl)amide

Guidance literature:: bis(trichloromethyl) carbonate; p-aminobenzophenone; With triethylamine; In acetonitrile; at -5 - 0 ℃; for 0.5h;

C₁₈H₁₈F₃NO₃; In acetonitrile; at 0 - 80 ℃; for 2h;