2-{4-(tert-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzoic acid

Base Information

Chemical Name:2-{4-(tert-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzoic acid
CAS No.:341519-85-5
Molecular Formula:C₃₃H₃₃NO₅Si
Molecular Weight:551.714
Hs Code.:

2-{4-(<i>tert</i>-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzoic acid

Synonyms:2-{4-(tert-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzoic acid

Suppliers and Price of 2-{4-(tert-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-{4-(tert-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-{4-(tert-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzoic acid

There total 12 articles about 2-{4-(tert-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 341519-84-4
2-{4-(tert-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzaldehyde

: 341519-85-5
2-{4-(tert-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzoic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In water; tert-butyl alcohol;
DOI:10.3987/com-00-s(i)58

Reference yield:

: 1144-74-7
4-nitrobenzophenone

: 341519-85-5
2-{4-(tert-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 45 percent / EtMgBr

2: 78 percent / NaOH; tetrabutylammonium iodide / benzene; H₂O

3: 72 percent / LiEt₃BH / tetrahydrofuran

4: 85 percent / PDC / CH₂Cl₂

5: 60 percent / NaClO₂; NaH₂PO₄; 2-methyl-2-butene / 2-methyl-propan-2-ol; H₂O

With sodium hydroxide; sodium chlorite; sodium dihydrogenphosphate; dipyridinium dichromate; 2-methyl-but-2-ene; ethylmagnesium bromide; tetra-(n-butyl)ammonium iodide; lithium triethylborohydride; In tetrahydrofuran; dichloromethane; water; tert-butyl alcohol; benzene;
DOI:10.3987/com-00-s(i)58

Reference yield:

: 612-14-6
phthalyl alcohol

: 341519-85-5
2-{4-(tert-butyl-dimethyl-silanyl)-1-[3-methoxy-3-(4-nitro-phenyl)-3-phenyl-prop-1-ynyl]-but-1-en-3-ynyl}-benzoic acid

Guidance literature:: Multi-step reaction with 11 steps

1: 65 percent / NaH / tetrahydrofuran

2: 79 percent / PDC / CH₂Cl₂

3: tetrahydrofuran

4: CrO₃; H₂SO₄ / acetone

5: 45 percent / Zn / tetrahydrofuran

6: 74 percent / MsCl; Et₃N / CH₂Cl₂

7: 45 percent / EtMgBr

8: 78 percent / NaOH; tetrabutylammonium iodide / benzene; H₂O

9: 72 percent / LiEt₃BH / tetrahydrofuran

10: 85 percent / PDC / CH₂Cl₂

11: 60 percent / NaClO₂; NaH₂PO₄; 2-methyl-2-butene / 2-methyl-propan-2-ol; H₂O

With chromium(VI) oxide; sodium hydroxide; sodium chlorite; sodium dihydrogenphosphate; dipyridinium dichromate; 2-methyl-but-2-ene; sulfuric acid; ethylmagnesium bromide; tetra-(n-butyl)ammonium iodide; sodium hydride; lithium triethylborohydride; methanesulfonyl chloride; triethylamine; zinc; In tetrahydrofuran; dichloromethane; water; acetone; tert-butyl alcohol; benzene;
DOI:10.3987/com-00-s(i)58