(4R,5S)-5-(2-Carboxy-phenylcarbamoyl)-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester

Base Information

• Chemical Name: (4R,5S)-5-(2-Carboxy-phenylcarbamoyl)-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester
• CAS No.: 199392-38-6
• Molecular Formula: C₂₄H₂₈N₂O₆
• Molecular Weight: 440.496

Synonyms:(4R,5S)-5-(2-Carboxy-phenylcarbamoyl)-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester

Chemical Property of (4R,5S)-5-(2-Carboxy-phenylcarbamoyl)-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4R,5S)-5-(2-Carboxy-phenylcarbamoyl)-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester

There total 3 articles about (4R,5S)-5-(2-Carboxy-phenylcarbamoyl)-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4R,5S)-5-(2-Methoxycarbonyl-phenylcarbamoyl)-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester → (4R,5S)-5-(2-Carboxy-phenylcarbamoyl)-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester (199392-38-6)

Guidance literature:

With lithium hydroxide; water; In tetrahydrofuran; methanol;

DOI:10.1016/S0960-894X(97)10010-5

Reference yield:

2-carbomethoxyaniline (134-20-3) → (4R,5S)-5-(2-Carboxy-phenylcarbamoyl)-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester (199392-38-6)

Guidance literature:

Multi-step reaction with 2 steps

1: DCC, HOBT / CH₂Cl₂ / 0 - 20 °C

2: LiOH, H₂O / methanol; tetrahydrofuran

With lithium hydroxide; water; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1016/S0960-894X(97)10010-5

Reference yield:

4R,5S-1-N-(tert-butoxycarbonyl)-2,2-dimethyl-4-phenyl-5-oxazolidinecarboxylic acid (223134-87-0) → (4R,5S)-5-(2-Carboxy-phenylcarbamoyl)-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester (199392-38-6)

Guidance literature:

Multi-step reaction with 2 steps

1: DCC, HOBT / CH₂Cl₂ / 0 - 20 °C

2: LiOH, H₂O / methanol; tetrahydrofuran

With lithium hydroxide; water; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1016/S0960-894X(97)10010-5

upstream raw materials:

2-carbomethoxyaniline

4R,5S-1-N-(tert-butoxycarbonyl)-2,2-dimethyl-4-phenyl-5-oxazolidinecarboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 199392-38-6 (4R,5S)-5-(2-Carboxy-phenylcarbamoyl)-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send