(1'R,2S)-2-(4'-methylenecyclohex-2'-en-1'-yl)propyl 4-nitrobenzenesulfonate

Base Information

Chemical Name:(1'R,2S)-2-(4'-methylenecyclohex-2'-en-1'-yl)propyl 4-nitrobenzenesulfonate
CAS No.:250689-37-3
Molecular Formula:C₁₆H₁₉NO₅S
Molecular Weight:337.397
Hs Code.:

Synonyms:(1'R,2S)-2-(4'-methylenecyclohex-2'-en-1'-yl)propyl 4-nitrobenzenesulfonate

Suppliers and Price of (1'R,2S)-2-(4'-methylenecyclohex-2'-en-1'-yl)propyl 4-nitrobenzenesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1'R,2S)-2-(4'-methylenecyclohex-2'-en-1'-yl)propyl 4-nitrobenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1'R,2S)-2-(4'-methylenecyclohex-2'-en-1'-yl)propyl 4-nitrobenzenesulfonate

There total 13 articles about (1'R,2S)-2-(4'-methylenecyclohex-2'-en-1'-yl)propyl 4-nitrobenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 252289-34-2
(1'R,2S)-2-(4'-methylenecyclohex-2'-en-1'-yl)propan-1-ol

: 250689-37-3
(1'R,2S)-2-(4'-methylenecyclohex-2'-en-1'-yl)propyl 4-nitrobenzenesulfonate

Guidance literature:: With pyridine; dmap; at 0 ℃; for 3h;
DOI:10.1002/(SICI)1522-2675(19991006)82:10<1610::AID-HLCA1610>3.0.CO;2-T

Reference yield:

: 13834-16-7
(1R,2S,5R)-2-[(S)-2-hydroxy-1-methylethyl]-5-methylcyclohexan-1-ol

: 250689-37-3
(1'R,2S)-2-(4'-methylenecyclohex-2'-en-1'-yl)propyl 4-nitrobenzenesulfonate

Guidance literature:: Multi-step reaction with 13 steps

1: 85 percent / 1H-imidazole / dimethylformamide / 15 h / 0 - 20 °C

2: 65 percent / (COCl)2; DMSO; Et₃N / CH₂Cl₂ / 3 h / -78 °C

3: 100 percent / BuLi; (i-Pr)2NH / hexane; tetrahydrofuran / 1 h / -78 °C

4: N-bromosuccinimide / tetrahydrofuran / 2 h / 0 °C

5: 70 percent / 2,4,6-trimethyl-pyridine / 1 h / 145 - 150 °C

6: 93 percent / H₂O₂; NaOH / methanol / 0 °C

7: 89 percent / CeCl₃*7H₂O; NaBH₄ / methanol / 1 h / 0 - 20 °C

8: 100 percent / Et₃N / tetrahydrofuran / 14 h / 0 - 20 °C

9: 90 percent / LiNEt₂ / tetrahydrofuran / 2 h / Heating

10: Et₃N / CH₂Cl₂ / 2 h / 0 °C

11: 63 percent / NaI; pyridine / acetone / 1 h / Heating

12: 90 percent / Bu₄NF*3H₂O / tetrahydrofuran / 14 h / 0 - 20 °C

13: 75 percent / pyridine; DMAP / 3 h / 0 °C

With pyridine; 1H-imidazole; dmap; sodium hydroxide; sodium tetrahydroborate; N-Bromosuccinimide; n-butyllithium; cerium(III) chloride; oxalyl dichloride; lithium diethylamide; tetrabutyl ammonium fluoride; dihydrogen peroxide; dimethyl sulfoxide; triethylamine; diisopropylamine; sodium iodide; In tetrahydrofuran; 2,4,6-trimethyl-pyridine; methanol; hexane; dichloromethane; N,N-dimethyl-formamide; acetone; 1: Substitution / 2: Oxidation / 3: Etherification / 4: Bromination / 5: Dehydrobromination / 6: Epoxidation / 7: Reduction / 8: Substitution / 9: Rearrangement / 10: Acylation / 11: Elimination / 12: Hydrolysis / 13: Acylation;
DOI:10.1002/(SICI)1522-2675(19991006)82:10<1610::AID-HLCA1610>3.0.CO;2-T

Reference yield:

: 252289-30-8
(1'R,2S)-dimethyl{[2-(4'-methylenecyclohex-2'-en-1'-yl)propyl]oxy}(1,1,2-trimethylpropyl)silane

: 250689-37-3
(1'R,2S)-2-(4'-methylenecyclohex-2'-en-1'-yl)propyl 4-nitrobenzenesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / Bu₄NF*3H₂O / tetrahydrofuran / 14 h / 0 - 20 °C

2: 75 percent / pyridine; DMAP / 3 h / 0 °C

With pyridine; dmap; tetrabutyl ammonium fluoride; In tetrahydrofuran; 1: Hydrolysis / 2: Acylation;
DOI:10.1002/(SICI)1522-2675(19991006)82:10<1610::AID-HLCA1610>3.0.CO;2-T