2-(4-bromophenyl)-2-oxoethyl hydroxyacetate

Base Information

• Chemical Name: 2-(4-bromophenyl)-2-oxoethyl hydroxyacetate
• CAS No.: 7404-31-1
• Molecular Formula: C₁₀H₉BrO₄
• Molecular Weight: 273.083
• Mol file: 7404-31-1.mol

Synonyms:

Chemical Property of 2-(4-bromophenyl)-2-oxoethyl hydroxyacetate

Chemical Property:

• Vapor Pressure: 2.1E-07mmHg at 25°C
• Boiling Point: 408.4°Cat760mmHg
• Flash Point: 200.8°C
• Density: 1.595g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-bromophenyl)-2-oxoethyl hydroxyacetate

There total 2 articles about 2-(4-bromophenyl)-2-oxoethyl hydroxyacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

glycolic Acid (79-14-1) + para-bromophenacyl bromide (99-73-0,132309-76-3) → Glycolic acid p-bromophenacyl ester (7404-31-1)

Guidance literature:

With sodium hydroxide; In ethanol; for 1h; Heating;

DOI:10.1039/b002504f

Reference yield:

→ Glycolic acid p-bromophenacyl ester (7404-31-1)

Guidance literature:

Na-Glykolat, 4-Brom-phenacylbromid, Erwaermen;

DOI:10.1246/bcsj.33.1458

Reference yield:

Glycolic acid p-bromophenacyl ester (7404-31-1) → Glycyl-glykolsaeure-<4-brom-phenacylester>

Guidance literature:

Multi-step reaction with 2 steps

1: imidazole

2: aq. HBr, AcOH

With 1H-imidazole; hydrogen bromide; acetic acid;

upstream raw materials:

glycolic Acid

para-bromophenacyl bromide