Technology Process of N-{(1S,2E)-4-(benzyloxy)-1-[(1S,2E)-3-iodo-1-methylprop-2-en-1-yl]-2-methylbut-2-en-1-yl}-2-nitroaniline
There total 8 articles about N-{(1S,2E)-4-(benzyloxy)-1-[(1S,2E)-3-iodo-1-methylprop-2-en-1-yl]-2-methylbut-2-en-1-yl}-2-nitroaniline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
triethylamine;
In
dichloromethane;
at 20 ℃;
for 3h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sulfuric acid; periodic acid / water; acetonitrile / 1.5 h / 20 °C
1.2: 8 h / 20 °C
2.1: Dess-Martin periodane / dichloromethane / 0.17 h / 20 °C
3.1: chromium dichloride / tetrahydrofuran / 5.5 h / 0 - 20 °C
4.1: hydrogenchloride / ethyl acetate / 1 h / 20 °C
5.1: triethylamine / dichloromethane / 3 h / 20 °C
With
chromium dichloride; hydrogenchloride; sulfuric acid; Dess-Martin periodane; periodic acid; triethylamine;
In
tetrahydrofuran; dichloromethane; water; ethyl acetate; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C
2.1: sulfuric acid; periodic acid / water; acetonitrile / 1.5 h / 20 °C
2.2: 8 h / 20 °C
3.1: Dess-Martin periodane / dichloromethane / 0.17 h / 20 °C
4.1: chromium dichloride / tetrahydrofuran / 5.5 h / 0 - 20 °C
5.1: hydrogenchloride / ethyl acetate / 1 h / 20 °C
6.1: triethylamine / dichloromethane / 3 h / 20 °C
With
chromium dichloride; hydrogenchloride; sulfuric acid; tetrabutyl ammonium fluoride; Dess-Martin periodane; periodic acid; triethylamine;
In
tetrahydrofuran; dichloromethane; water; ethyl acetate; acetonitrile;