N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5(hydroxymethyl)tetra hydro-furan-2-yl)-9H-purin-6-yl)benzamide

Base Information

• Chemical Name: N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5(hydroxymethyl)tetra hydro-furan-2-yl)-9H-purin-6-yl)benzamide
• CAS No.: 1142928-71-9
• Molecular Formula: C₂₃H₃₀N₈O₄Si
• Molecular Weight: 510.628

Synonyms:N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5(hydroxymethyl)tetra hydro-furan-2-yl)-9H-purin-6-yl)benzamide

Chemical Property of N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5(hydroxymethyl)tetra hydro-furan-2-yl)-9H-purin-6-yl)benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5(hydroxymethyl)tetra hydro-furan-2-yl)-9H-purin-6-yl)benzamide

There total 11 articles about N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5(hydroxymethyl)tetra hydro-furan-2-yl)-9H-purin-6-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5-((tert-butyldimethyl silyloxy)-methyl)-tetrahydrofuran-2-yl)-9H-purin-6-yl)-N-benzoylbenzamide (1142928-64-0) → N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5(hydroxymethyl)tetra hydro-furan-2-yl)-9H-purin-6-yl)benzamide (1142928-71-9)

Guidance literature:

With water; trifluoroacetic acid; at 0 ℃; for 3h;

DOI:10.5012/bkcs.2010.31.6.1643

Reference yield: 74.0%

6-N-benzoyl-3′-azido-2′,5′-bis-O-(tert-butyldimethylsilyl)-3′-deoxyadenosine (1142928-70-8) → N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5(hydroxymethyl)tetra hydro-furan-2-yl)-9H-purin-6-yl)benzamide (1142928-71-9)

Guidance literature:

With water; trifluoroacetic acid; In tetrahydrofuran; at 0 ℃; for 8h;

DOI:10.1002/chem.200801563

Reference yield:

C44H48N8O6Si → N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5(hydroxymethyl)tetra hydro-furan-2-yl)-9H-purin-6-yl)benzamide (1142928-71-9)

Guidance literature:

With dichloro-acetic acid; In dichloromethane; at 20 ℃;

upstream raw materials:

6-N-benzoyl-3′-azido-2′,5′-bis-O-(tert-butyldimethylsilyl)-3′-deoxyadenosine

N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5-((tert-butyldimethyl silyloxy)-methyl)-tetrahydrofuran-2-yl)-9H-purin-6-yl)-N-benzoylbenzamide

adenosine

2',5'-bis-O-(tert-butyldimethylsilyl)adenosine

Downstream raw materials:

C₃₂H₄₅N₉O₆Si

C₃₈H₄₉N₉O₆Si

diphenyl (E)-2-((2R,3R,4R,5R)-3-azido-5-(6-benzamido-9H-purin-9-yl)-4-(tert-butyldimethylsilyloxy)-tetrahydrofuran-2-yl)vinylphosphonate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1142928-71-9 N-(9-((2R,3R,4R,5S)-4-azido-3-(tert-butyldimethylsilyloxy)-5(hydroxymethyl)tetra hydro-furan-2-yl)-9H-purin-6-yl)benzamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send