4,4,5,5-tetramethyl-2-(3-phenylprop-2-yn-1-yl)-1,3,2-dioxaborolane

Base Information

• Chemical Name: 4,4,5,5-tetramethyl-2-(3-phenylprop-2-yn-1-yl)-1,3,2-dioxaborolane
• CAS No.: 1425747-00-7
• Molecular Formula: C₁₅H₁₉BO₂
• Molecular Weight: 242.126
• Mol file: 1425747-00-7.mol

Synonyms:4,4,5,5-tetramethyl-2-(3-phenylprop-2-yn-1-yl)-1,3,2-dioxaborolane

Chemical Property of 4,4,5,5-tetramethyl-2-(3-phenylprop-2-yn-1-yl)-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4,5,5-tetramethyl-2-(3-phenylprop-2-yn-1-yl)-1,3,2-dioxaborolane

There total 2 articles about 4,4,5,5-tetramethyl-2-(3-phenylprop-2-yn-1-yl)-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

phenylacetylene (536-74-3) + pinacol (bromomethyl)boronate (166330-03-6) → 4,4,5,5-tetramethyl-2-(3-phenylprop-2-yn-1-yl)-1,3,2-dioxaborolane (1425747-00-7)

Guidance literature:

phenylacetylene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

pinacol (bromomethyl)boronate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2h;

DOI:10.1149/2.0561702jes

Reference yield:

2-(iodomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (70557-99-2) + phenylacetylene (536-74-3) → 4,4,5,5-tetramethyl-2-(3-phenylprop-2-yn-1-yl)-1,3,2-dioxaborolane (1425747-00-7)

Guidance literature:

phenylacetylene; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 1h;

2-(iodomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1039/C8RA09600G

Reference yield: 98.0%

4,4,5,5-tetramethyl-2-(3-phenylprop-2-yn-1-yl)-1,3,2-dioxaborolane (1425747-00-7) + benzaldehyde (100-52-7) → 1,2-diphenyl-2,3-butadien-1-ol (165335-53-5)

Guidance literature:

With MIL-101-SO₃H; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1039/C8RA09600G

upstream raw materials:

phenylacetylene

pinacol (bromomethyl)boronate

2-(iodomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Downstream raw materials:

2-(4-chlorophenyl)-3-phenylpenta-3,4-dien-2-ol

Phenylpropargyl aldehyde

(3-methoxyprop-1-yn-1-yl)benzene

3-Phenyl-2-propyn-1-ol