N,N'-bis(2-hydroxy-3-methoxyphenylmethylidene)-2,3-pyridinediamine

Base Information

• Chemical Name: N,N'-bis(2-hydroxy-3-methoxyphenylmethylidene)-2,3-pyridinediamine
• CAS No.: 376355-02-1
• Molecular Formula: C₂₁H₁₉N₃O₄
• Molecular Weight: 377.4
• Mol file: 376355-02-1.mol

Synonyms:N,N'-bis(2-hydroxy-3-methoxyphenylmethylidene)-2,3-pyridinediamine

Chemical Property of N,N'-bis(2-hydroxy-3-methoxyphenylmethylidene)-2,3-pyridinediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of N,N'-bis(2-hydroxy-3-methoxyphenylmethylidene)-2,3-pyridinediamine

There total 1 articles about N,N'-bis(2-hydroxy-3-methoxyphenylmethylidene)-2,3-pyridinediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

2,3-Diaminopyridine (452-58-4) + 3-methoxy-2-hydroxybenzaldehyde (148-53-8) → N,N'-bis(2-hydroxy-3-methoxyphenylmethylidene)-2,3-pyridinediamine (376355-02-1)

Guidance literature:

In methanol;

DOI:10.1080/00958972.2013.849343

Reference yield: 43.0%

tris(triphenylphosphine)ruthenium(II) chloride (15529-49-4,41756-81-4) + N,N'-bis(2-hydroxy-3-methoxyphenylmethylidene)-2,3-pyridinediamine (376355-02-1) + water (7732-18-5) → [Ru(H2O)(triphenylphosphine)(C5H3N(NCHC6H3(OCH3)O)2)] dihydrate

Guidance literature:

With triethylamine; In tetrahydrofuran; byproducts: NEt3*HCl; addn. of RuCl2(PPh3)3 (1 equiv.) to soln. of C5H3N(NCHC6H3(OH)(OCH3))2 (1 equiv.) and triethylamine in THF; stirring at room temp. for 3 h; pptn., filtration, concn. of filtrate in vac., addn. of diethyl ether, pptn., recrystn. from THF; elem. anal.;

upstream raw materials:

2,3-Diaminopyridine

3-methoxy-2-hydroxybenzaldehyde