Technology Process of C19H18Cl2N2O2
There total 3 articles about C19H18Cl2N2O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 24h;
DOI:10.1002/anie.201100495
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tetrabutylammomium bromide / tetrahydrofuran / 24 h / 60 °C
2: sodium hydroxide / tetrahydrofuran; water / 3 h / 20 °C
3: benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 24 h / 0 - 20 °C
With
tetrabutylammomium bromide; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; sodium hydroxide;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1002/anie.201100495
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydroxide / tetrahydrofuran; water / 3 h / 20 °C
2: benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 24 h / 0 - 20 °C
With
benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; sodium hydroxide;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1002/anie.201100495