N-(5,8-bisbenzyloxy-2-methyl-1,2-dihydronaphthalen-1-yl)-4-methylbenzenesulfonate

Base Information

• Chemical Name: N-(5,8-bisbenzyloxy-2-methyl-1,2-dihydronaphthalen-1-yl)-4-methylbenzenesulfonate
• CAS No.: 1158650-12-4
• Molecular Formula: C₃₂H₃₁NO₄S
• Molecular Weight: 525.668
• Mol file: 1158650-12-4.mol

Synonyms:N-(5,8-bisbenzyloxy-2-methyl-1,2-dihydronaphthalen-1-yl)-4-methylbenzenesulfonate

Chemical Property of N-(5,8-bisbenzyloxy-2-methyl-1,2-dihydronaphthalen-1-yl)-4-methylbenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of N-(5,8-bisbenzyloxy-2-methyl-1,2-dihydronaphthalen-1-yl)-4-methylbenzenesulfonate

There total 1 articles about N-(5,8-bisbenzyloxy-2-methyl-1,2-dihydronaphthalen-1-yl)-4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

5,8-bisbenzyloxy-9-(4-toluenesulfonyl)-1,4-dihydro-1,4-epiazanonaphthalene + dimethyl zinc(II) (544-97-8) → N-(5,8-bisbenzyloxy-2-methyl-1,2-dihydronaphthalen-1-yl)-4-methylbenzenesulfonate (1158650-12-4)

Guidance literature:

With Pd2I2(μ-t-Bu-MiniPHOS)2; silver trifluoromethanesulfonate; In hexane; toluene; at 80 ℃; for 1h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/ol900533h

Reference yield:

N-(5,8-bisbenzyloxy-2-methyl-1,2-dihydronaphthalen-1-yl)-4-methylbenzenesulfonate (1158650-12-4) + diethylzinc (557-20-0) → Et(EtZn)TsN(C10H6)(OBn)2

Guidance literature:

In hexane; 2 equiv. of Me2Zn, room temp., 1 h;

DOI:10.1039/b902602a

Reference yield:

N-(5,8-bisbenzyloxy-2-methyl-1,2-dihydronaphthalen-1-yl)-4-methylbenzenesulfonate (1158650-12-4) + dimethyl zinc(II) (544-97-8) → Me(MeZn)TsN(C10H6)(OBn)2

Guidance literature:

In hexane; 2 equiv. of Me2Zn, room temp., 1 h;

DOI:10.1039/b902602a

upstream raw materials:

dimethyl zinc(II)