Carbamic acid, ((1S,2S,4R)-5-(((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)amino)-2-hydroxy-5-oxo-1,4-bis(phenylmethyl)pentyl)-, (3S)-tetrahydro-3-furanyl ester

Base Information

Chemical Name:Carbamic acid, ((1S,2S,4R)-5-(((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)amino)-2-hydroxy-5-oxo-1,4-bis(phenylmethyl)pentyl)-, (3S)-tetrahydro-3-furanyl ester
CAS No.:145631-03-4
Molecular Formula:C₃₃H₃₈N₂O₆
Molecular Weight:558.675
Hs Code.:
DSSTox Substance ID:DTXSID80163122
Nikkaji Number:J528.726J
Wikidata:Q83031976
ChEMBL ID:CHEMBL319408
Mol file:145631-03-4.mol

Carbamic acid, ((1S,2S,4R)-5-(((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)amino)-2-hydroxy-5-oxo-1,4-bis(phenylmethyl)pentyl)-, (3S)-tetrahydro-3-furanyl ester

Synonyms:CHEMBL319408;145631-03-4;Carbamic acid, ((1S,2S,4R)-5-(((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)amino)-2-hydroxy-5-oxo-1,4-bis(phenylmethyl)pentyl)-, (3S)-tetrahydro-3-furanyl ester;N-(2(R)-Hydroxy-1(S)-indanyl)-5-(S)-(((3(S)-tetrahydrofuranyloxy)carbonyl)amino)-4(S)-hydroxy-6-phenyl-2(R)-benzylhexanamide;Urethane deriv. 2;Carbamic acid, [(1S,2S,4R)-5-[[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]amino]-2-hydroxy-5-oxo-1,4-bis(phenylmethyl)pentyl]-, (3S)-tetrahydro-3-furanyl ester;N-[2(R)-Hydroxy-1(S)-indanyl]-5-(S)-[[(3(S)-tetrahydrofuranyloxy)carbonyl]amino]-4(S)-hydroxy-6-phenyl-2(R)-benzylhexanamide;SCHEMBL7295897;DTXSID80163122;BDBM50562071;(2R,4S,5S)-N-[(1S,2R)-2-Hydroxyindan-1-yl]-2-benzyl-4-hydroxy-5-[[[(S)-3-oxolanyloxy]carbonyl]amino]-6-phenylhexanamide;[(3S)-tetrahydrofuran-3-yl] N-[(1S,2S,4R)-1,4-dibenzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxyindan-1-yl]amino]-5-oxo-pentyl]carbamate

Suppliers and Price of Carbamic acid, ((1S,2S,4R)-5-(((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)amino)-2-hydroxy-5-oxo-1,4-bis(phenylmethyl)pentyl)-, (3S)-tetrahydro-3-furanyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Carbamic acid, ((1S,2S,4R)-5-(((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)amino)-2-hydroxy-5-oxo-1,4-bis(phenylmethyl)pentyl)-, (3S)-tetrahydro-3-furanyl ester

Chemical Property:

Vapor Pressure:4.27E-30mmHg at 25°C
Boiling Point:841.8°Cat760mmHg
Flash Point:462.9°C
Density:1.28g/cm³
XLogP3:3.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:12
Exact Mass:558.27298694
Heavy Atom Count:41
Complexity:829

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCC1OC(=O)NC(CC2=CC=CC=C2)C(CC(CC3=CC=CC=C3)C(=O)NC4C(CC5=CC=CC=C45)O)O
Isomeric SMILES:C1COC[C@H]1OC(=O)N[C@@H](CC2=CC=CC=C2)[C@H](C[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H]4[C@@H](CC5=CC=CC=C45)O)O

Technology Process of Carbamic acid, ((1S,2S,4R)-5-(((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)amino)-2-hydroxy-5-oxo-1,4-bis(phenylmethyl)pentyl)-, (3S)-tetrahydro-3-furanyl ester

There total 5 articles about Carbamic acid, ((1S,2S,4R)-5-(((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)amino)-2-hydroxy-5-oxo-1,4-bis(phenylmethyl)pentyl)-, (3S)-tetrahydro-3-furanyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 126456-36-8
L-685434

: 145631-03-4,145680-03-1
[(1S,2S,4R)-1-Benzyl-2-hydroxy-4-((1S,2R)-2-hydroxy-indan-1-ylcarbamoyl)-5-phenyl-pentyl]-carbamic acid (R)-(tetrahydro-furan-3-yl) ester

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / CH₂Cl₂ / 0.5 h / 0 °C

2: triethylamine / CH₂Cl₂

With triethylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jm00054a015

Reference yield:

: 126456-36-8
L-685434

: 145631-03-4,145680-03-1
N-(2(R)-hydroxy-1(S)-indanyl)-5(S)-(3(S)-tetrahydrofuranyloxycarbonylamino)-4(S)-hydroxy-6-phenyl-2(R)-phenylmethyl hexanamide

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / CH₂Cl₂ / 0.5 h / 0 °C

2: triethylamine / CH₂Cl₂

With triethylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jm00054a015