5-(m-(Trifluoromethyl)benzyl)hydantoin

Base Information

• Chemical Name: 5-(m-(Trifluoromethyl)benzyl)hydantoin
• CAS No.: 76605-52-2
• Molecular Formula: C11H9F3N2O2
• Molecular Weight: 258.2
• DSSTox Substance ID: DTXSID90997935
• Nikkaji Number: J77.755B
• ChEMBL ID: CHEMBL139929
• Mol file: 76605-52-2.mol

Synonyms:BRN 5078595;5-(m-(Trifluoromethyl)benzyl)hydantoin;Hydantoin, 5-(m-(trifluoromethyl)benzyl)-;76605-52-2;C11H9F3N2O2;5-[m-(Trifluoromethyl)benzyl]hydantoin;CHEMBL139929;DTXSID90997935;LS-76299;4-{[3-(Trifluoromethyl)phenyl]methyl}-4H-imidazole-2,5-diol

Chemical Property of 5-(m-(Trifluoromethyl)benzyl)hydantoin

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.391g/cm³
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 258.06161202
• Heavy Atom Count: 18
• Complexity: 357

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)C(F)(F)F)CC2C(=O)NC(=O)N2

Technology Process of 5-(m-(Trifluoromethyl)benzyl)hydantoin

There total 1 articles about 5-(m-(Trifluoromethyl)benzyl)hydantoin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

5-(3-trifluoromethylbenzylidene)imidazoline-2,4-dione (76605-42-0) → 5-(3-Trifluoromethyl-benzyl)-imidazolidine-2,4-dione (76605-52-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1021/jm00136a018

upstream raw materials:

5-(3-trifluoromethylbenzylidene)imidazoline-2,4-dione