<<1-(4-chlorophenyl)-1H-tetrazol-5-yl>thio>-ethyl acetate

Base Information

• Chemical Name: <<1-(4-chlorophenyl)-1H-tetrazol-5-yl>thio>-ethyl acetate
• CAS No.: 115781-87-8
• Molecular Formula: C₁₁H₁₁ClN₄O₂S
• Molecular Weight: 298.753
• Mol file: 115781-87-8.mol

Synonyms:<<1-(4-chlorophenyl)-1H-tetrazol-5-yl>thio>-ethyl acetate

Chemical Property of <<1-(4-chlorophenyl)-1H-tetrazol-5-yl>thio>-ethyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <<1-(4-chlorophenyl)-1H-tetrazol-5-yl>thio>-ethyl acetate

There total 1 articles about <<1-(4-chlorophenyl)-1H-tetrazol-5-yl>thio>-ethyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1-(4-chlorophenyl)-1H-tetrazole-5-thiol (27143-76-6) + chloroacetic acid ethyl ester (105-39-5) → <<1-(4-chlorophenyl)-1H-tetrazol-5-yl>thio>-ethyl acetate (115781-87-8)

Guidance literature:

With sodium hydroxide;

DOI:10.1016/j.carres.2011.01.010

Reference yield: 66.0%

<<1-(4-chlorophenyl)-1H-tetrazol-5-yl>thio>-ethyl acetate (115781-87-8) → <<1-(4-chlorophenyl)-1H-tetrazol-5-yl>thio>-acetic acid hydrazide (115781-88-9)

Guidance literature:

With hydrazine hydrate; In ethanol; for 10h; Heating;

Reference yield:

<<1-(4-chlorophenyl)-1H-tetrazol-5-yl>thio>-ethyl acetate (115781-87-8) → 5-(1-(4-chlorophenyl)-1H-tetrazol-5-ylsulfanylmethyl)-N-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-1,3,4-oxadiazol-2-amine (1231978-15-6)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine hydrate / ethanol / 4 h / Reflux

2: benzene / 4 h / Reflux

3: mercury(II) diacetate / ethanol / Reflux

With mercury(II) diacetate; hydrazine hydrate; In ethanol; benzene;

DOI:10.1016/j.carres.2011.01.010

upstream raw materials:

1-(4-chlorophenyl)-1H-tetrazole-5-thiol

chloroacetic acid ethyl ester

Downstream raw materials:

<<1-(4-chlorophenyl)-1H-tetrazol-5-yl>thio>-acetic acid hydrazide

5-(1-(4-chlorophenyl)-1H-tetrazol-5-ylsulfanylmethyl)-N-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-1,3,4-oxadiazol-2-amine

5-(1-(4-chlorophenyl)-1H-tetrazol-5-ylsulfanylmethyl)-N-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-1,3,4-thiadiazol-2-amine

5-(1-(4-chlorophenyl)-1H-tetrazol-5-ylsulfanylmethyl)-N-β-D-xylopyranosyl-1,3,4-oxadiazol-2-amine