methyl (3-(3-(6-fluoroimidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methylcarbamate

Base Information

Chemical Name:methyl (3-(3-(6-fluoroimidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methylcarbamate
CAS No.:1426669-90-0
Molecular Formula:C₂₀H₁₇FN₆O₄
Molecular Weight:424.391
Hs Code.:

Synonyms:methyl (3-(3-(6-fluoroimidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methylcarbamate

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Chemical Property of methyl (3-(3-(6-fluoroimidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methylcarbamate

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Technology Process of methyl (3-(3-(6-fluoroimidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methylcarbamate

There total 2 articles about methyl (3-(3-(6-fluoroimidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1019021-85-2
6-fluoroimidazo[1,2-a]pyridine-3-carboxylic acid

: 1426671-34-2
methyl (3-(3-amino-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methylcarbamate

: 1426669-90-0
methyl (3-(3-(6-fluoroimidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methylcarbamate

Guidance literature:: 6-fluoroimidazo[1,2-a]pyridine-3-carboxylic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 ℃; for 1.5h; Inert atmosphere;

methyl (3-(3-amino-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methylcarbamate; With pyridine; at 0 - 20 ℃; for 0.333333h;

Reference yield:

: ((3-(4-methyl-3-nitrophenyl)-1,2,4-oxadiazol-5-yl)methyl)carbamate

: 1426669-90-0
methyl (3-(3-(6-fluoroimidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / ethanol / 0.42 h / 78 °C

2.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1.5 h / 0 °C / Inert atmosphere

2.2: 0.33 h / 0 - 20 °C

With oxalyl dichloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; In ethanol; dichloromethane;