serratamic acid

Base Information

• Chemical Name: serratamic acid
• CAS No.: 541-81-1
• Molecular Formula: C₁₃H₂₅NO₅
• Molecular Weight: 275.345
• Hs Code.: 2924199090
• Mol file: 541-81-1.mol

Synonyms:L-Serine,N-(3-hydroxy-1-oxodecyl)-, (R)-; Serine, N-(D-3-hydroxydecanoyl)-, L-(7CI,8CI); Serratamic acid (6CI)

Chemical Property of serratamic acid

Chemical Property:

• Vapor Pressure: 1.45E-13mmHg at 25°C
• Boiling Point: 532.6°Cat760mmHg
• Flash Point: 275.9°C
• PSA: 106.86000
• Density: 1.149g/cm³
• LogP: 1.05050

Purity/Quality:

99%, ^*data from raw suppliers

SerratamicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Serratamic Acid provides resistance to phagocytosis by human polymorphonuclear leukocytes.

Technology Process of serratamic acid

There total 8 articles about serratamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3R)-3-hydroxydecanoic acid (19525-80-5) → Serrataminsaeure (541-81-1)

Guidance literature:

Multi-step reaction with 4 steps

1: Ag₂O / diethyl ether

2: DCC / CH₂Cl₂

3: H₂ / Pd / methanol

4: aq. Na₂CO₃

With hydrogen; sodium carbonate; dicyclohexyl-carbodiimide; silver(l) oxide; palladium; In methanol; diethyl ether; dichloromethane;

DOI:10.1007/BF00564122

Reference yield:

3-hydroxydecanoic acid (5561-87-5,19525-80-5,19526-23-9,33044-91-6,14292-26-3) → Serrataminsaeure (541-81-1)

Guidance literature:

Multi-step reaction with 5 steps

2: Ag₂O / diethyl ether

3: DCC / CH₂Cl₂

4: H₂ / Pd / methanol

5: aq. Na₂CO₃

With hydrogen; sodium carbonate; dicyclohexyl-carbodiimide; silver(l) oxide; palladium; In methanol; diethyl ether; dichloromethane;

DOI:10.1007/BF00564122

Reference yield:

(R)-3-(benzyloxy)decanoic acid (19525-83-8) → Serrataminsaeure (541-81-1)

Guidance literature:

Multi-step reaction with 3 steps

1: DCC / CH₂Cl₂

2: H₂ / Pd / methanol

3: aq. Na₂CO₃

With hydrogen; sodium carbonate; dicyclohexyl-carbodiimide; palladium; In methanol; dichloromethane;

DOI:10.1007/BF00564122

upstream raw materials:

Ser-OMe

N-((R)-3-hydroxy-decanoyl)-L-serine methyl ester

(S)-serine methyl ester

(3R)-3-hydroxydecanoic acid

Downstream raw materials:

methyl (R)-3-hydroxydecanoate