4-(N-methylbenzylamino)-3-methyl-1-(p-tosyl)indole-6,7-dione

Base Information

• Chemical Name: 4-(N-methylbenzylamino)-3-methyl-1-(p-tosyl)indole-6,7-dione
• CAS No.: 937208-17-8
• Molecular Formula: C₂₄H₂₂N₂O₄S
• Molecular Weight: 434.516
• Mol file: 937208-17-8.mol

Synonyms:4-(N-methylbenzylamino)-3-methyl-1-(p-tosyl)indole-6,7-dione

Chemical Property of 4-(N-methylbenzylamino)-3-methyl-1-(p-tosyl)indole-6,7-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(N-methylbenzylamino)-3-methyl-1-(p-tosyl)indole-6,7-dione

There total 1 articles about 4-(N-methylbenzylamino)-3-methyl-1-(p-tosyl)indole-6,7-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzyl-methyl-amine (103-67-3) + 3-methyl-1-(p-tosyl)indole-6,7-dione (760213-05-6) → 4-(N-methylbenzylamino)-3-methyl-1-(p-tosyl)indole-6,7-dione (937208-17-8)

Guidance literature:

In acetonitrile; at 20 ℃; for 48h;

DOI:10.1021/jo0700272

Reference yield:

4-(N-methylbenzylamino)-3-methyl-1-(p-tosyl)indole-6,7-dione (937208-17-8) → C24H24N2O4S (937208-18-9)

Guidance literature:

With methylhydrazine; In acetonitrile; for 48h;

DOI:10.1021/jo0700272

Reference yield:

4-(N-methylbenzylamino)-3-methyl-1-(p-tosyl)indole-6,7-dione (937208-17-8) → C17H18N2O2

Guidance literature:

Multi-step reaction with 3 steps

1: CH₃NHNH₂ / acetonitrile / 48 h

2: aq. NaOH / ethanol / 0.17 h / 20 °C

3: CH₃NHNH₂ / acetonitrile

With sodium hydroxide; methylhydrazine; In ethanol; acetonitrile;

DOI:10.1021/jo0700272

upstream raw materials:

benzyl-methyl-amine

3-methyl-1-(p-tosyl)indole-6,7-dione

Downstream raw materials:

C₂₄H₂₄N₂O₄S

4-(N-methylbenzylamino)-3-methylindole-6,7-dione