1,5-bis(4-nitrophenyl)-1H-1,2,3-triazole

Base Information

• Chemical Name: 1,5-bis(4-nitrophenyl)-1H-1,2,3-triazole
• CAS No.: 31802-49-0
• Molecular Formula: C₁₄H₉N₅O₄
• Molecular Weight: 311.257
• Mol file: 31802-49-0.mol

Synonyms:1,5-bis(4-nitrophenyl)-1H-1,2,3-triazole

Chemical Property of 1,5-bis(4-nitrophenyl)-1H-1,2,3-triazole

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of 1,5-bis(4-nitrophenyl)-1H-1,2,3-triazole

There total 4 articles about 1,5-bis(4-nitrophenyl)-1H-1,2,3-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

p-nitrobenzene iodide (636-98-6) + 1-(4-nitrophenyl)-1H-1,2,3-triazole (1204-91-7) → 1,5-bis(4-nitrophenyl)-1H-1,2,3-triazole (31802-49-0)

Guidance literature:

With C₁₈H₁₆N₂O₄Pd; caesium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 16h; regioselective reaction;

DOI:10.1080/00397911.2017.1381260

Reference yield: 38.0%

1,5-bis-(4-nitro-phenyl)-4,5-dihydro-1H-[1,2,3]triazole (10480-04-3) → 1,5-bis(4-nitrophenyl)-1H-1,2,3-triazole (31802-49-0)

Guidance literature:

With potassium permanganate; tetrabutyl-ammonium chloride; In water; benzene; for 8h; Heating;

Reference yield:

4-nitrophenyl azide (1516-60-5) → 1,5-bis(4-nitrophenyl)-1H-1,2,3-triazole (31802-49-0)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(II) sulfate; sodium L-ascorbate; potassium carbonate / methanol; water / 24 h / 20 °C / Inert atmosphere

2: caesium carbonate; tris-(o-tolyl)phosphine; palladium diacetate / N,N-dimethyl-formamide / 20.25 h / 20 - 100 °C / Inert atmosphere

With palladium diacetate; potassium carbonate; caesium carbonate; copper(II) sulfate; sodium L-ascorbate; tris-(o-tolyl)phosphine; In methanol; water; N,N-dimethyl-formamide;

DOI:10.1021/jo5026145

upstream raw materials:

1,5-bis-(4-nitro-phenyl)-4,5-dihydro-1H-[1,2,3]triazole

p-nitrobenzene iodide

1-(4-nitrophenyl)-1H-1,2,3-triazole

4-nitrophenyl azide