4-tert-butyl-N'-(2-chloroacetyl)benzohydrazide

Base Information

Chemical Name:4-tert-butyl-N'-(2-chloroacetyl)benzohydrazide
CAS No.:874594-88-4
Molecular Formula:C₁₃H₁₇ClN₂O₂
Molecular Weight:268.743
Hs Code.:
DSSTox Substance ID:DTXSID701182806

Synonyms:4-tert-butyl-N'-(2-chloroacetyl)benzohydrazide;874594-88-4;4-tert-butyl-N'-(chloroacetyl)benzohydrazide;DTXSID701182806;AKOS000118183;UPCMLD0ENAT5474617:001;CS-0239764;EN300-21861;Z147433182;4-(1,1-Dimethylethyl)benzoic acid 2-(2-chloroacetyl)hydrazide

Suppliers and Price of 4-tert-butyl-N'-(2-chloroacetyl)benzohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-tert-butyl-N'-(2-chloroacetyl)benzohydrazide

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:268.0978555
Heavy Atom Count:18
Complexity:305

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=CC=C(C=C1)C(=O)NNC(=O)CCl

Technology Process of 4-tert-butyl-N'-(2-chloroacetyl)benzohydrazide

There total 3 articles about 4-tert-butyl-N'-(2-chloroacetyl)benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 43100-38-5
4-tert-butylbenzoic acid hydrazide

: 79-11-8
chloroacetic acid

: 874594-88-4
PCM-0102355

Guidance literature:: chloroacetic acid; With 2,6-dimethylpyridine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; In dichloromethane; at 25 ℃; for 0.166667h;

4-tert-butylbenzoic acid hydrazide; at 20 ℃; for 3h;
DOI:10.1002/ardp.201300240

Reference yield:

: 98-73-7
4-(1,1-dimethylethyl)benzoic acid

: 874594-88-4
PCM-0102355

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate; chloroformic acid ethyl ester / dichloromethane / 0 - 5 °C

2: ethyl acetate / Reflux

With chloroformic acid ethyl ester; hydrazine hydrate; In dichloromethane; ethyl acetate;
DOI:10.5935/0103-5053.20130275