o-acetoxyphenyl isothiocyanate

Base Information

• Chemical Name: o-acetoxyphenyl isothiocyanate
• CAS No.: 72695-34-2
• Molecular Formula: C₉H₇NO₂S
• Molecular Weight: 193.226
• Mol file: 72695-34-2.mol

Synonyms:o-acetoxyphenyl isothiocyanate

Chemical Property of o-acetoxyphenyl isothiocyanate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of o-acetoxyphenyl isothiocyanate

There total 3 articles about o-acetoxyphenyl isothiocyanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

acetic anhydride (108-24-7) + (2-hydroxy-phenyl)-dithiocarbamic acid → o-acetoxyphenyl isothiocyanate (72695-34-2)

Guidance literature:

With triethylamine; In water; at 20 ℃; for 0.0333333h;

DOI:10.1080/00397910008087301

Reference yield:

2-amino-phenol (95-55-6) → o-acetoxyphenyl isothiocyanate (72695-34-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / H₂O / 1 h / 20 °C

2: 54 percent / Et₃N / H₂O / 0.03 h / 20 °C

With triethylamine; In water; 1: Condensation / 2: Acetylation;

DOI:10.1080/00397910008087301

Reference yield:

→ o-acetoxyphenyl isothiocyanate (72695-34-2)

Guidance literature:

2-Methylbenzoxazol (2), Thiophosgen, CaCO3;

upstream raw materials:

acetic anhydride

2-amino-phenol