(2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-tridecanediol

Base Information

Chemical Name:(2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-tridecanediol
CAS No.:1314766-51-2
Molecular Formula:C₆₂H₁₀₈N₂O₁₂
Molecular Weight:1073.55
Hs Code.:

Synonyms:(2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-tridecanediol

Suppliers and Price of (2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-tridecanediol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-tridecanediol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-tridecanediol

There total 10 articles about (2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-tridecanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₆₂H₁₀₆N₂O₁₂

: 1314766-51-2
(2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-tridecanediol

Guidance literature:: With sodium cyanoborohydride; In methanol; at 20 ℃; for 2h;
DOI:10.1016/j.tet.2011.05.054

Reference yield:

: 1314766-43-2
(2S,3S)-3-O-benzyl-2-tert-butyloxycarbonylamino-3-(thiazol-2-yl)-1,3-propanediol

: 1314766-51-2
(2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-tridecanediol

Guidance literature:: Multi-step reaction with 7 steps

1.1: dichloromethane / 1 h / Molecular sieve; Inert atmosphere

1.2: 3 h / -15 °C / Inert atmosphere; Molecular sieve

2.1: trifluoroacetic acid / dichloromethane / 3 h

3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

4.1: acetonitrile / 12 h / Reflux

5.1: sodium tetrahydroborate / methanol / 0.58 h / 0 - 20 °C

5.2: 1 h / 20 °C

6.1: methanol / 2 h / 20 °C

7.1: sodium cyanoborohydride / methanol / 2 h / 20 °C

With sodium tetrahydroborate; sodium cyanoborohydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.tet.2011.05.054

Reference yield:

: 1314766-44-3
(2S,3S)-3-O-benzyl-2-tert-butyloxycarbonylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-3-(thiazol-2-yl)-1,3-propanediol

: 1314766-51-2
(2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-tridecanediol

Guidance literature:: Multi-step reaction with 6 steps

1.1: trifluoroacetic acid / dichloromethane / 3 h

2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

3.1: acetonitrile / 12 h / Reflux

4.1: sodium tetrahydroborate / methanol / 0.58 h / 0 - 20 °C

4.2: 1 h / 20 °C

5.1: methanol / 2 h / 20 °C

6.1: sodium cyanoborohydride / methanol / 2 h / 20 °C

With sodium tetrahydroborate; sodium cyanoborohydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.tet.2011.05.054