p-methylphenyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside

Base Information

• Chemical Name: p-methylphenyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside
• CAS No.: 258333-93-6
• Molecular Formula: C₂₄H₂₆O₇S
• Molecular Weight: 458.532
• Mol file: 258333-93-6.mol

Synonyms:p-methylphenyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside

Chemical Property of p-methylphenyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-methylphenyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside

There total 4 articles about p-methylphenyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

acetic anhydride (108-24-7) + p-methylphenyl 4,6-O-benzylidene-1-thio-β-D-galactopyranoside (220645-86-3) → p-methylphenyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside (258333-93-6)

Guidance literature:

With pyridine;

DOI:10.1021/ja982232s

Reference yield: 77.0%

p-methylphenyl-1-thio-β-D-galactopyranoside (1152-39-2,28244-98-6,121523-95-3,131488-68-1) + benzaldehyde dimethyl acetal (1125-88-8) + acetic anhydride (108-24-7) → p-methylphenyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside (258333-93-6)

Guidance literature:

p-methylphenyl-1-thio-β-D-galactopyranoside; benzaldehyde dimethyl acetal; With toluene-4-sulfonic acid; In acetonitrile; at 25 ℃; Inert atmosphere;

acetic anhydride; In acetonitrile; at 40 ℃; Inert atmosphere;

DOI:10.1055/s-0028-1087913

Reference yield:

p-methylphenyl-1-thio-β-D-galactopyranoside (1152-39-2,28244-98-6,121523-95-3,131488-68-1) → p-methylphenyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside (258333-93-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / camphorsulfonic acid / acetonitrile / 2 h / Ambient temperature

2: 97 percent / pyridine

With pyridine; camphor-10-sulfonic acid; In acetonitrile;

DOI:10.1021/ja982232s

upstream raw materials:

acetic anhydride

p-methylphenyl 4,6-O-benzylidene-1-thio-β-D-galactopyranoside

p-methylphenyl-1-thio-β-D-galactopyranoside

benzaldehyde dimethyl acetal

Downstream raw materials:

toluyl 2,3-di-O-acetyl-4-O-benzyl-1-thio-β-D-galactopyranose