toluyl 2,3-di-O-acetyl-4-O-benzyl-1-thio-β-D-galactopyranose

Base Information

• Chemical Name: toluyl 2,3-di-O-acetyl-4-O-benzyl-1-thio-β-D-galactopyranose
• CAS No.: 1453169-57-7
• Molecular Formula: C₂₄H₂₈O₇S
• Molecular Weight: 460.548
• Mol file: 1453169-57-7.mol

Synonyms:toluyl 2,3-di-O-acetyl-4-O-benzyl-1-thio-β-D-galactopyranose

Chemical Property of toluyl 2,3-di-O-acetyl-4-O-benzyl-1-thio-β-D-galactopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of toluyl 2,3-di-O-acetyl-4-O-benzyl-1-thio-β-D-galactopyranose

There total 2 articles about toluyl 2,3-di-O-acetyl-4-O-benzyl-1-thio-β-D-galactopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

toluyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranose → toluyl 2,3-di-O-acetyl-4-O-benzyl-1-thio-β-D-galactopyranose (1453169-57-7)

Guidance literature:

With triethylsilane; phenylborondichloride; In dichloromethane; at -78 ℃; for 0.25h; Inert atmosphere; Molecular sieve;

DOI:10.1002/ejoc.201300664

Reference yield:

p-methylphenyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside (258333-93-6) → toluyl 2,3-di-O-acetyl-4-O-benzyl-1-thio-β-D-galactopyranose (1453169-57-7)

Guidance literature:

With borane-THF; di-n-butylboryl trifluoromethanesulfonate; In tetrahydrofuran; dichloromethane; at 0 ℃; for 1.16667h; Inert atmosphere;

DOI:10.1039/c9ob00108e

Reference yield:

toluyl 2,3-di-O-acetyl-4-O-benzyl-1-thio-β-D-galactopyranose (1453169-57-7) + Allyl chloroformate (2937-50-0) → toluyl 2,3-di-O-acetyl-4-O-benzyl-6-O-allyloxycarbonyl-1-thio-β-D-galactopyranoside (1453169-56-6)

Guidance literature:

With pyridine; In dichloromethane; at 0 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1002/ejoc.201300664

upstream raw materials:

p-methylphenyl 2,3-di-O-acetyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside

Downstream raw materials:

toluyl 2,3-di-O-acetyl-4-O-benzyl-6-O-allyloxycarbonyl-1-thio-β-D-galactopyranoside