1-chloro-2-cyclohexylethyne

Base Information

• Chemical Name: 1-chloro-2-cyclohexylethyne
• CAS No.: 50284-86-1
• Molecular Formula: C₈H₁₁Cl
• Molecular Weight: 142.628
• Mol file: 50284-86-1.mol

Synonyms:1-chloro-2-cyclohexylethyne

Chemical Property of 1-chloro-2-cyclohexylethyne

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-chloro-2-cyclohexylethyne

There total 4 articles about 1-chloro-2-cyclohexylethyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-cyclohexylacetylene (931-48-6) → 1-chloro-2-cyclohexylethyne (50284-86-1)

Guidance literature:

With N-chloro-succinimide; n-butyllithium; In tetrahydrofuran;

Reference yield:

2-cyclohexyl-1,1-dichloroethylene (56772-65-7) → 1-chloro-2-cyclohexylethyne (50284-86-1)

Guidance literature:

With n-butyllithium; diethylamine; In tetrahydrofuran; diethyl ether;

DOI:10.1055/s-1975-23805

Reference yield:

cyclohexanecarbaldehyde (2043-61-0) → 1-chloro-2-cyclohexylethyne (50284-86-1)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) nBuLi, Et₂O, THF, (ii) /BRN= 878306/

2: nBuLi, Et₂NH / diethyl ether; tetrahydrofuran

With n-butyllithium; diethylamine; In tetrahydrofuran; diethyl ether;

DOI:10.1055/s-1975-23805

upstream raw materials:

dichloroethyne

cyclohexylmagnesiumchloride

2-cyclohexyl-1,1-dichloroethylene

2-cyclohexylacetylene

Downstream raw materials:

1,4-dicyclohexylbuta-1,3-diyne

cyclohexyl-oxo-acetic acid methyl ester

(1E,3E)-1-cyclohexyl-1,3-octadiene

(Z)-1-bromo-1-chloro-2-cyclohexylethene