Technology Process of C33H38O8S
There total 17 articles about C33H38O8S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
-
-
(2S,3S,4aR,5R,7R,8S,8aS)-8-Benzyloxy-2,3-dimethoxy-5-{2-[5-(4-methoxy-phenoxymethyl)-dihydro-furan-(2Z)-ylidene]-ethyl}-7-(2-methoxy-phenylsulfanyl)-2,3-dimethyl-hexahydro-pyrano[3,4-b][1,4]dioxine
- Guidance literature:
-
With
water; trifluoroacetic acid;
In
dichloromethane;
Yield given;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 84 percent / Ph3P, DEAD / tetrahydrofuran / Heating
2: 98 percent / DIBAL-H / toluene / -78 °C
3: acetonitrile
4: NaOH / H2O / Heating
5: 1.) LDA, 2.) t-BuOK / 1.) THF, -78 deg C, 2.) THF, -78 deg C to r.t.
6: H2O, TFA / CH2Cl2
With
sodium hydroxide; potassium tert-butylate; water; diisobutylaluminium hydride; triphenylphosphine; trifluoroacetic acid; lithium diisopropyl amide; diethylazodicarboxylate;
In
tetrahydrofuran; dichloromethane; water; toluene; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 87 percent / BF3*Et2O / CH2Cl2
2: 100 percent / K2CO3, MeOH
3: 68 percent / CSA / methanol / Heating
4: 95 percent / NaH / dimethylformamide
5: Et3N / CH2Cl2 / -78 °C
6: dimethylformamide; acetonitrile
7: 90 percent / DIBAL-H / toluene / -78 °C
8: 1.) LDA, 2.) t-BuOK / 1.) THF, -78 deg C, 2.) THF, -78 deg C to r.t.
9: H2O, TFA / CH2Cl2
With
methanol; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; potassium tert-butylate; water; sodium hydride; diisobutylaluminium hydride; potassium carbonate; triethylamine; trifluoroacetic acid; lithium diisopropyl amide;
In
methanol; dichloromethane; N,N-dimethyl-formamide; toluene; acetonitrile;