1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]piperidine-2-carboxylic acid

Base Information

Chemical Name:1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]piperidine-2-carboxylic acid
CAS No.:1393450-93-5
Molecular Formula:C₂₇H₃₇NO₃
Molecular Weight:423.596
Hs Code.:

Synonyms:1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]piperidine-2-carboxylic acid

Suppliers and Price of 1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]piperidine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]piperidine-2-carboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]piperidine-2-carboxylic acid

There total 3 articles about 1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]piperidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 0.8%

: 1266115-60-9
6-(trans-4-tert-butylcyclohexyloxy)-2-naphthaldehyde

: 15862-86-9,5107-10-8
piperidine-2-carboxylic acid hydrochloride

: 1393450-93-5
1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]piperidine-2-carboxylic acid

Guidance literature:: 6-(trans-4-tert-butylcyclohexyloxy)-2-naphthaldehyde; piperidine-2-carboxylic acid hydrochloride; With acetic acid; In 1,2-dichloro-ethane; Reflux;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane;

Reference yield:

: 15231-91-1
6-bromo-naphthalen-2-ol

: 1393450-93-5
1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]piperidine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: caesium carbonate / butanone; tert-butyl alcohol / 0.17 h / 110 °C

1.2: 15 h / 110 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere

2.2: 1 h / -78 °C

2.3: pH 6

3.1: acetic acid / 1,2-dichloro-ethane / Reflux

With n-butyllithium; caesium carbonate; acetic acid; In tetrahydrofuran; 1,2-dichloro-ethane; butanone; tert-butyl alcohol;

Reference yield:

: 1225352-09-9
2-bromo-6-(trans-4-tert-butylcyclohexyloxy)naphthalene

: 1393450-93-5
1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]piperidine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere

1.2: 1 h / -78 °C

1.3: pH 6

2.1: acetic acid / 1,2-dichloro-ethane / Reflux

With n-butyllithium; acetic acid; In tetrahydrofuran; 1,2-dichloro-ethane;