1266115-60-9

Upstream product

• 1266116-03-3 6-(trans-4-tert-butylcyclohexyloxy)naphthalen-2-ylmethanol 
• 1266116-02-2 methyl 6-(trans-4-tert-butylcyclohexyloxy)-2-naphthoate 
• 18508-91-3 methanesulfonic acid 4-tert-butylcyclohexyl ester 
• 17295-11-3 methyl 6-hydroxynaphthalene-2-carboxylate 
• 937-05-3 cis-4-tert-butyl-1-cyclohexanol 
• 18508-90-2 trans-4-tert-butylmesyloxycyclohexane 
• 15231-91-1 6-bromo-naphthalen-2-ol 
• 1225352-09-9 2-bromo-6-(trans-4-tert-butylcyclohexyloxy)naphthalene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1393450-93-5 1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]piperidine-2-carboxylic acid 
• 1393449-29-0 ethyl 1-((6-(trans-4-tert-butylcyclohexyloxy)naphthalen-2-yl)methyl)-4-methylpiperidine-4-carboxylate 
• 1393449-30-3 1-((6-(trans-4-tert-butylcyclohexyloxy)naphthalen-2-yl)methyl)-4-methylpiperidine-4-carboxylic acid 
• 1393449-56-3 1-[6-(4-tert-butylcyclohexyloxy)naphthalen-2-ylmethyl]-3-methylpiperidine-4-carboxylic acid 
• 1393449-55-2 ethyl 1-((6-((trans-4-(tert-butyl)cyclohexyl)oxy)naphthalen-2-yl)methyl)-3-methylpiperidine-4-carboxylate 
• 1266116-25-9 {[6-(trans-4-tert-butyl-cyclohexyloxy)-naphthalen-2-ylmethyl]-amino}-acetic acid ethyl ester 
• 1266116-17-9 (S)-methyl 1-((6-(trans-4-tert-butylcyclohexyloxy)naphthalen-2-yl)methyl)piperidine-3-carboxylate 
• 1266115-76-7 ethyl 2-(((6-(trans-4-tert-butylcyclohexyloxy)naphthalen-2-yl)methyl)(methyl)amino)acetate 
• 1266116-20-4 4-{[6-(trans-4-tert-butyl-cyclohexyloxy)-naphthalen-2-ylmethyl]-amino}-butyric acid tert-butyl ester 
• 1266116-64-6 3-((6-((trans)-4-tert-butylcyclohexyloxy)naphthalen-2-yl)methylamino)-N-(methylsulfonyl)propanamide 
• 1266119-72-5 (R)-1-[6-(4-tert-butyl-cyclohexyloxy)-naphthalen-2-ylmethyl]-pyrrolidine-3-carboxylic acid 
• 1266119-00-9 1-((6-((trans)-4-tert-butylcyclohexyloxy)naphthalen-2-yl)methyl)-4-methylpyrrolidine-3-carboxylic acid 
• 1266116-26-0 {[6-(trans-4-tert-butyl-cyclohexyloxy)-naphthalen-2-ylmethyl]-amino}-acetic acid 
• 1266116-28-2 (2-{[6-(trans-4-tert-butyl-cyclohexyloxy)-naphthalen-2-ylmethyl]-amino}-ethyl)-phosphonic acid diethyl ester 

Relevant academic research and scientific papers

COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS

Compounds of formula (I) can modulate the activity of one or more S1P receptors and/or the activity of autotaxin (ATX).

S1P MODULATING AGENTS

Compounds of formula (I) or (II) can modulate the activity of SIP receptors.

BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS

Compounds that have agonist activity at one or more of the SlP receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at SlP receptors.