Chemical Property of Enprofylline
Chemical Property:
- Refractive Index:1.583
- PSA：83.54000
- Density:1.367 g/cm3
- LogP:-0.17710
- Storage Temp.:2-8°C
- Solubility.:DMSO: soluble
- XLogP3:0.3
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:2
- Exact Mass:194.08037557
- Heavy Atom Count:14
- Complexity:268
- Purity/Quality:
-
97% *data from raw suppliers
Enprofylline *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn
- Hazard Codes:Xn
- Statements:
20/21/22
- Safety Statements:
36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CCCN1C2=C(C(=O)NC1=O)NC=N2
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Description
3-Propylxanthine is a xanthine derivative that antagonizes adenosine receptors (Kis = 44, 32, and 6.3 μM for A1, A2A, and A2B, respectively) and cAMP phosphodiesterase (Ki = 42 μM). Through these actions, 3-propylxanthine induces smooth muscle relaxation, blocks smooth muscle contraction and VEGF secretion driven by adenosine receptor agonists, and reduces bronchial hyperresponsiveness.
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Uses
Bronchodilator. Enprofylline is a xanthine lacking adenosine receptor antagonism.
