14036-06-7

Basic information

• Product Name: Diethoxymethyl acetate
• Synonyms: Diethoxymethyleacetate;diethoxy-methanoacetate;ACETIC ACID DIETHOXYMETHYL ESTER;METHYL 2,2-DIETHOXYACETATE;DIETHOXYMETHYL ACETATE;methanol, diethoxy-, acetate;Nsc158267;Diethoxymethyl acetate ,97%
• CAS NO: 14036-06-7
• Molecular Formula: C₇H₁₄O₄
• Molecular Weight: 162.18
• EINECS: 237-873-4
• Product Categories: Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;C6 to C7;Carbonyl Compounds;Esters;Building Blocks;C6 to C7
• Mol File: 14036-06-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 185.7 °C at 760 mmHg
• Flash Point: 82 °F
• Appearance: Clear colorless/Liquid
• Density: 0.993 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.689mmHg at 25°C
• Refractive Index: n20/D 1.399(lit.)
• Storage Temp.: 2-8°C
• BRN: 1209886
• CAS DataBase Reference: Diethoxymethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Diethoxymethyl acetate(14036-06-7)
• EPA Substance Registry System: Diethoxymethyl acetate(14036-06-7)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 16-26-36/37/39
• RIDADR: UN 3272 3/PG 3
• WGK Germany: 3
• F: 9-21
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 14036-06-7(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

Uses

Diethoxymethyl acetate was used in the synthesis of D-mannosyl, D-galactosyl and D-glucosyl theophylline nucleosides.

General Description

Diethoxymethyl acetate reacts with 5-amino-6-ribitylaminouracil hydrochloride to yield 6-dioxo-(1H,3H)-9-N-ribitylpurine.

InChI:InChI=1/C7H14O4/c1-4-9-7(10-5-2)11-6(3)8/h7H,4-5H2,1-3H3

Upstream product

• 108-24-7 acetic anhydride 
• 122-51-0 orthoformic acid triethyl ester 
• 64-19-7 acetic acid 

Downstream Products

• 64-17-5 ethanol 
• 127-09-3 sodium acetate 
• 109-94-4 formic acid ethyl ester 
• 905-96-4 3,3'-diethyloxacarbocyanine iodide 
• 15979-19-8 3-ethyl-2-(3-{3-[3-(3-ethyl-3H-benzothiazol-2-ylidenemethyl)-5,5-dimethyl-cyclohex-2-enylidene]-propenyl}-5,5-dimethyl-cyclohex-2-enylidenemethyl)-benzothiazolium; iodide 
• 15900-11-5 (5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-pyrazol-4-ylidene)-methane 
• 3788-94-1 2-ethoxymethylene-3-oxobutanoic acid ethyl ester 
• 5427-23-6 9-Ethylpurine 
• 64-19-7 acetic acid 
• 864131-95-3 N,N'-diphenylformamidine 
• 5462-86-2 6-chloro-9-ethyl-9H-purine 
• 17997-33-0 diethyl(diethoxymethyl)phosphonate 
• 7252-55-3 acetic acid-(α-ethoxy-isobutyl ester) 
• 25604-54-0 1-chloro-4-diethoxymethoxy-benzene 

Relevant articles and documents

Substitution of the acetoxy groups of dialkoxymethylacetates by organometallic reagents: a route to allyl-, propargyl-, homoallyl-, homopropargyl- and α-stannylacetals

The substitution of the acetoxy groups of dialkoxymethylacetates by organometallic reagents has been examined in a search for new methods of preparing functional acetals.The efficiency of the substitution of the acetoxy group is highly dependent on the nature of the organometallic reagents: soft nucleophiles with strong electrophilic assistance by the counterion are the best reagents.Allyl-, propargyl-, homoallyl-, homopropargyl- and α-stannylacetals have been made by this route, in which dialkoxymethylacetates often function as useful substitutes for dialkylphenylorthoformates.