3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-oxo-pentyl]-N-methyl-benzamide

Base Information

• Chemical Name: 3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-oxo-pentyl]-N-methyl-benzamide
• CAS No.: 484697-88-3
• Molecular Formula: C₂₀H₁₈Cl₄N₂O₃
• Molecular Weight: 476.187
• Mol file: 484697-88-3.mol

Synonyms:3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-oxo-pentyl]-N-methyl-benzamide

Chemical Property of 3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-oxo-pentyl]-N-methyl-benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-oxo-pentyl]-N-methyl-benzamide

There total 8 articles about 3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-oxo-pentyl]-N-methyl-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-5-hydroxy-2-methoxyimino-pentyl]-N-methyl-benzamide (484697-86-1) → 3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-oxo-pentyl]-N-methyl-benzamide (484697-88-3)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane;

DOI:10.1016/S0960-894X(02)00340-2

Reference yield:

3,5-dichlorobenzoyl chloride (2905-62-6) → 3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-oxo-pentyl]-N-methyl-benzamide (484697-88-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 97 percent / pyridine / CH₂Cl₂

2: 80 percent / hydrofluoric acid / acetonitrile

3: 100 percent / mercuric perchlorate; CaCO₃; H₂O / tetrahydrofuran

4: 28 percent / pyridine

5: 100 percent / oxalyl chloride; DMSO; Et₃N / CH₂Cl₂

With pyridine; mercury(II) perchlorate; oxalyl dichloride; hydrogen fluoride; water; dimethyl sulfoxide; triethylamine; calcium carbonate; In tetrahydrofuran; dichloromethane; acetonitrile;

DOI:10.1016/S0960-894X(02)00340-2

Reference yield:

{2-[3-(tert-butyl-dimethyl-silanyloxy)-1-(3,4-dichloro-phenyl)-propyl]-[1,3]dithiolan-2-yl}-methanol (184969-89-9) → 3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-oxo-pentyl]-N-methyl-benzamide (484697-88-3)

Guidance literature:

Multi-step reaction with 7 steps

1: 100 percent / oxalyl chloride; DMSO; Et₃N / CH₂Cl₂

2: 44 percent / NaCNBH₃ / 2,2,2-trifluoro-ethanol

3: 97 percent / pyridine / CH₂Cl₂

4: 80 percent / hydrofluoric acid / acetonitrile

5: 100 percent / mercuric perchlorate; CaCO₃; H₂O / tetrahydrofuran

6: 28 percent / pyridine

7: 100 percent / oxalyl chloride; DMSO; Et₃N / CH₂Cl₂

With pyridine; mercury(II) perchlorate; oxalyl dichloride; hydrogen fluoride; water; sodium cyanoborohydride; dimethyl sulfoxide; triethylamine; calcium carbonate; In tetrahydrofuran; dichloromethane; 2,2,2-trifluoroethanol; acetonitrile; 1: Swern oxidation;

DOI:10.1016/S0960-894X(02)00340-2

upstream raw materials:

3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-5-hydroxy-2-methoxyimino-pentyl]-N-methyl-benzamide

3,5-dichlorobenzoyl chloride

{2-[3-(tert-butyl-dimethyl-silanyloxy)-1-(3,4-dichloro-phenyl)-propyl]-[1,3]dithiolan-2-yl}-methanol

2-[3-(tert-butyl-dimethyl-silanyloxy)-1-(3,4-dichloro-phenyl)-propyl]-[1,3]dithiolane-2-carbaldehyde

Downstream raw materials:

3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-(3-methylcarbamoylmethyl-2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide

3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-(3-methylcarbamoylmethyl-2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide

3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-(3-methylcarbamoylmethyl-2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide

3,5-dichloro-N-[3-(3,4-dichloro-phenyl)-2-methoxyimino-5-(3-methylcarbamoylmethyl-2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide