Technology Process of 7-methyl-7-phenyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione
There total 6 articles about 7-methyl-7-phenyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
ammonium hydroxide;
In
water;
at 80 ℃;
for 4h;
Sealed tube;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: diethyl ether; tetrahydrofuran / 2.5 h / 0 °C / Reflux
1.2: Cooling with ice
2.1: formic acid; dihydrogen peroxide / 4 h / 20 °C
3.1: sodium hydride / 1,2-dimethoxyethane; mineral oil / 1 h / 0 °C
3.2: 2 h / Reflux
4.1: toluene / 2.75 h / 58 - 130 °C / Inert atmosphere; Sealed tube
5.1: ammonium hydroxide / 4 h / 80 °C / Sealed tube
With
ammonium hydroxide; formic acid; dihydrogen peroxide; sodium hydride;
In
tetrahydrofuran; 1,2-dimethoxyethane; diethyl ether; toluene; mineral oil;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: diethyl ether; tetrahydrofuran / 2.5 h / 0 °C / Reflux
1.2: Cooling with ice
2.1: formic acid; dihydrogen peroxide / 4 h / 20 °C
3.1: sodium hydride / 1,2-dimethoxyethane; mineral oil / 1 h / 0 °C
3.2: 2 h / Reflux
4.1: toluene / 2.75 h / 58 - 130 °C / Inert atmosphere; Sealed tube
5.1: ammonium hydroxide / 4 h / 80 °C / Sealed tube
With
ammonium hydroxide; formic acid; dihydrogen peroxide; sodium hydride;
In
tetrahydrofuran; 1,2-dimethoxyethane; diethyl ether; toluene; mineral oil;