Technology Process of C37H40N6O5
There total 8 articles about C37H40N6O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-(tert-butoxycarbonyl)-L-proline; C27H25N5O2;
With
N-ethyl-N,N-diisopropylamine;
In
acetonitrile;
at 20 ℃;
for 0.166667h;
With
HATU;
In
acetonitrile;
at 20 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: dmap / acetonitrile; tetrahydrofuran / 0 - 25 °C
2.1: lithium diisopropyl amide; Triisopropyl borate / tetrahydrofuran / 2 h / 0 - 25 °C
2.2: pH 3
3.1: sodium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; tetrahydrofuran / 75 °C / Inert atmosphere
4.1: hydrogenchloride / methanol / 16 h
5.1: HATU; N-ethyl-N,N-diisopropylamine / acetonitrile / 25 °C
With
hydrogenchloride; dmap; tetrakis(triphenylphosphine) palladium(0); Triisopropyl borate; sodium carbonate; N-ethyl-N,N-diisopropylamine; HATU; lithium diisopropyl amide;
In
tetrahydrofuran; methanol; water; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: HATU; N-ethyl-N,N-diisopropylamine / acetonitrile / 25 °C
2: acetic acid / 4 h / 100 °C
3: sodium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; tetrahydrofuran / 75 °C / Inert atmosphere
4: hydrogenchloride / methanol / 16 h
5: HATU; N-ethyl-N,N-diisopropylamine / acetonitrile / 25 °C
With
hydrogenchloride; tetrakis(triphenylphosphine) palladium(0); sodium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; HATU;
In
tetrahydrofuran; methanol; water; acetonitrile;