5-(2',4'-Difluoro(1,1'-biphenyl)-4-yl)-5-hydroxy-3-methyl-2(5H)-furanone

Base Information

Chemical Name:5-(2',4'-Difluoro(1,1'-biphenyl)-4-yl)-5-hydroxy-3-methyl-2(5H)-furanone
CAS No.:170950-57-9
Molecular Formula:C17H12F2O3
Molecular Weight:302.2722
Hs Code.:
DSSTox Substance ID:DTXSID70937910
Mol file:170950-57-9.mol

Synonyms:170950-57-9;5-(2',4'-Difluoro(1,1'-biphenyl)-4-yl)-5-hydroxy-3-methyl-2(5H)-furanone;5-[4-(2,4-difluorophenyl)phenyl]-5-hydroxy-3-methylfuran-2-one;2(5H)-Furanone, 5-(2',4'-difluoro(1,1'-biphenyl)-4-yl)-5-hydroxy-3-methyl-;DTXSID70937910;GBSBGNSXWCMNQM-UHFFFAOYSA-N;LS-70367;5-(2',4'-Difluoro[1,1'-biphenyl]-4-yl)-5-hydroxy-3-methylfuran-2(5H)-one

Suppliers and Price of 5-(2',4'-Difluoro(1,1'-biphenyl)-4-yl)-5-hydroxy-3-methyl-2(5H)-furanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-(2',4'-DIFLUORO(1,1'-BIPHENYL)-4-YL)-5-HYDROXY-3-METHYL-2(5H)-FURANONE 95.00%
5MG
$ 495.25

Total 1 raw suppliers

Chemical Property of 5-(2',4'-Difluoro(1,1'-biphenyl)-4-yl)-5-hydroxy-3-methyl-2(5H)-furanone

Chemical Property:

Boiling Point:487°Cat760mmHg
Flash Point:248.3°C
PSA：46.53000
Density:1.368g/cm³
LogP:3.28000
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:302.07545056
Heavy Atom Count:22
Complexity:471

Purity/Quality:: 5-(2',4'-DIFLUORO(1,1'-BIPHENYL)-4-YL)-5-HYDROXY-3-METHYL-2(5H)-FURANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(OC1=O)(C2=CC=C(C=C2)C3=C(C=C(C=C3)F)F)O

Technology Process of 5-(2',4'-Difluoro(1,1'-biphenyl)-4-yl)-5-hydroxy-3-methyl-2(5H)-furanone

There total 2 articles about 5-(2',4'-Difluoro(1,1'-biphenyl)-4-yl)-5-hydroxy-3-methyl-2(5H)-furanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.6%

: (E)-4-(2',4'-difluorobiphenyl-4-yl)-2-methyl-4-oxobut-2-enoic acid

: 170950-57-9
5-(2',4'-Difluoro-biphenyl-4-yl)-5-hydroxy-3-methyl-5H-furan-2-one

Guidance literature:: In diethyl ether; at 20 ℃; for 48h;
DOI:10.1135/cccc19951026

Reference yield:

: 161692-81-5
4-(2',4'-difluorobiphenyl-4-yl)-2-methylene-4-oxobutanoic acid

: 170950-57-9
5-(2',4'-Difluoro-biphenyl-4-yl)-5-hydroxy-3-methyl-5H-furan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / triethylamine / H₂O / 8 h / 20 °C

2: 59.6 percent / diethyl ether / 48 h / 20 °C

With triethylamine; In diethyl ether; water;
DOI:10.1135/cccc19951026