N-(4-nitro-2-pyridyl)-3-trifluoromethylbenzamide

Base Information

• Chemical Name: N-(4-nitro-2-pyridyl)-3-trifluoromethylbenzamide
• CAS No.: 1021358-44-0
• Molecular Formula: C₁₃H₈F₃N₃O₃
• Molecular Weight: 311.22
• Mol file: 1021358-44-0.mol

Synonyms:N-(4-nitro-2-pyridyl)-3-trifluoromethylbenzamide

Chemical Property of N-(4-nitro-2-pyridyl)-3-trifluoromethylbenzamide

Chemical Property:

Purity/Quality:

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Technology Process of N-(4-nitro-2-pyridyl)-3-trifluoromethylbenzamide

There total 1 articles about N-(4-nitro-2-pyridyl)-3-trifluoromethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

2-chloro-4-nitropyridine (23056-36-2) + 3-trifluoromethylbenzamide (1801-10-1) → N-(4-nitro-2-pyridyl)-3-trifluoromethylbenzamide (1021358-44-0)

Guidance literature:

With caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; Heating;

DOI:10.1021/jm701191z

Reference yield: 85.0%

N-(4-nitro-2-pyridyl)-3-trifluoromethylbenzamide (1021358-44-0) → C13H10F3N3O (1021358-48-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; under 750.075 Torr;

DOI:10.1021/jm701191z

upstream raw materials:

2-chloro-4-nitropyridine

3-trifluoromethylbenzamide

Downstream raw materials:

C₁₃H₁₀F₃N₃O

Refernces