L-phenylalanyllaurylamide hydrochloride

Base Information

• Chemical Name: L-phenylalanyllaurylamide hydrochloride
• CAS No.: 73048-85-8
• Molecular Formula: C₂₁H₃₆N₂O*ClH
• Molecular Weight: 368.991
• Mol file: 73048-85-8.mol

Synonyms:L-phenylalanyllaurylamide hydrochloride

Chemical Property of L-phenylalanyllaurylamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of L-phenylalanyllaurylamide hydrochloride

There total 4 articles about L-phenylalanyllaurylamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

Boc-Phe-NH-(CH2)11-CH3 → L-phenylalanyllaurylamide hydrochloride (73048-85-8)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃;

DOI:10.1002/pep2.24155

Reference yield:

n-Dodecylamine (124-22-1) → L-phenylalanyllaurylamide hydrochloride (73048-85-8)

Guidance literature:

Multi-step reaction with 2 steps

1: benzotriazol-1-ol; dicyclohexyl-carbodiimide / N,N-dimethyl-formamide / -5 - 20 °C

2: hydrogenchloride / ethyl acetate / 20 °C

With hydrogenchloride; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.12.051

Reference yield:

N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) → L-phenylalanyllaurylamide hydrochloride (73048-85-8)

Guidance literature:

Multi-step reaction with 2 steps

1: benzotriazol-1-ol; dicyclohexyl-carbodiimide / N,N-dimethyl-formamide / -5 - 20 °C

2: hydrogenchloride / ethyl acetate / 20 °C

With hydrogenchloride; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.12.051

upstream raw materials:

n-Dodecylamine

N-tert-butoxycarbonyl-L-phenylalanine

Boc-Phe-ONSu

Downstream raw materials:

C₃₇H₆₄N₄O₆

C₆₅H₉₈Cl₂N₈O₁₂

C₆₅H₁₀₀N₈O₁₂

C₆₅H₉₈Cl₂N₈O₁₂