Technology Process of (3S,7S)-1-(benzyloxy)-3,7-dimethyldecane
There total 13 articles about (3S,7S)-1-(benzyloxy)-3,7-dimethyldecane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium amalgam;
In
ethanol;
for 40h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 27.0 g / NaH / 1,2-dimethoxy-ethane
2: 89 percent / Ph2Se2, H2O2, t-BuOOH
3: 1.) O3; 2.) NaBH4 / 1.) CH2Cl2, CH3OH
4: pyridine
5: NaI / acetone
6: 91 percent / dimethylformamide / 12 h / Ambient temperature
7: 1.) n-BuLi / 1.) hexane, THF, HMPA, -30 deg C, 1 h; 2.) hexane, THF, HMPA, r.t., 12 h
8: 81 percent / Na-Hg / ethanol / 40 h / Ambient temperature
With
pyridine; tert.-butylhydroperoxide; sodium tetrahydroborate; n-butyllithium; sodium amalgam; diphenyl diselenide; dihydrogen peroxide; sodium hydride; ozone; sodium iodide;
In
1,2-dimethoxyethane; ethanol; N,N-dimethyl-formamide; acetone;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: pyridine / 12 h / 0 - 5 °C
2: NaI / acetone / 1.) reflux, 5 h; 2.) r.t., 12 h
3: 1.) n-BuLi / 1.) hexane, THF, HMPA, -30 deg C, 1 h; 2.) hexane, THF, HMPA, r.t., 12 h
4: 81 percent / Na-Hg / ethanol / 40 h / Ambient temperature
With
pyridine; n-butyllithium; sodium amalgam; sodium iodide;
In
ethanol; acetone;
