C₂₅H₂₇F₁₇O₅

Base Information

• Chemical Name: C₂₅H₂₇F₁₇O₅
• CAS No.: 1585235-85-3
• Molecular Formula: C₂₅H₂₇F₁₇O₅
• Molecular Weight: 730.459
• Mol file: 1585235-85-3.mol

Synonyms:C₂₅H₂₇F₁₇O₅

Chemical Property of C₂₅H₂₇F₁₇O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₂₇F₁₇O₅

There total 11 articles about C₂₅H₂₇F₁₇O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

15-(4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl)-1,1,1-triphenyl-2,5,8,11,14-pentaoxapentadecane (1585235-84-2) → C25H27F17O5 (1585235-85-3)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; at 20 ℃;

DOI:10.1016/j.tetlet.2014.02.047

Reference yield:

2-(n-perfluorooctyl)ethyl iodide (2043-53-0,71215-70-8) → C25H27F17O5 (1585235-85-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate / 1,2-dimethoxyethane; water / 24 h / 90 °C / Inert atmosphere

2.1: phosphorus tribromide / dichloromethane / 2 h / 0 - 20 °C

3.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 20 °C / Inert atmosphere

3.2: 12 h / 20 °C / Inert atmosphere

4.1: toluene-4-sulfonic acid / methanol / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; phosphorus tribromide; sodium hydride; sodium hydrogencarbonate; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane; water; mineral oil; 1.1: |Suzuki Coupling;

DOI:10.1016/j.tetlet.2014.02.047

Reference yield:

1,4-bromoiodobenzene (589-87-7) → C25H27F17O5 (1585235-85-3)

Guidance literature:

Multi-step reaction with 6 steps

1.1: chloro-trimethyl-silane; zinc / tetrahydrofuran / 15.15 h / 30 °C / Inert atmosphere

1.2: 12 h / 45 °C / Inert atmosphere

2.1: n-butyllithium; N,N-dimethyl-formamide / tetrahydrofuran / 2.5 h / -40 °C / Inert atmosphere

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C

4.1: phosphorus tribromide / dichloromethane / 2 h / 0 - 20 °C

5.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 20 °C / Inert atmosphere

5.2: 12 h / 20 °C / Inert atmosphere

6.1: toluene-4-sulfonic acid / methanol / 20 °C

With lithium aluminium tetrahydride; n-butyllithium; chloro-trimethyl-silane; phosphorus tribromide; sodium hydride; toluene-4-sulfonic acid; N,N-dimethyl-formamide; zinc; In tetrahydrofuran; methanol; dichloromethane; mineral oil;

DOI:10.1016/j.tetlet.2014.02.047

upstream raw materials:

15-(4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl)-1,1,1-triphenyl-2,5,8,11,14-pentaoxapentadecane

2-(n-perfluorooctyl)ethyl iodide

1,4-bromoiodobenzene

1-(4'-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecane

Downstream raw materials:

27-(4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl)-1,1,1-triphenyl-2,5,8,11,14,17,20,23,26-nonaoxaheptacosane

((3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl)-2,5,8,11,14,17,20,23-octaoxapentacosan-25-ol

9-(4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl)-1,1,1-triphenyl-2,5,8,11,14,17,20,23,26,29,32,35,38-tridecaoxanonatriacontane

Refernces