Technology Process of 15-(4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl)-1,1,1-triphenyl-2,5,8,11,14-pentaoxapentadecane
There total 11 articles about 15-(4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl)-1,1,1-triphenyl-2,5,8,11,14-pentaoxapentadecane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
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1-(bromomethyl)-4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)benzene
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1585235-84-2
15-(4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl)-1,1,1-triphenyl-2,5,8,11,14-pentaoxapentadecane
- Guidance literature:
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1,1,1-triphenyl-2,5,8,11-tetraoxatridecan-13-ol;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
for 0.166667h;
Inert atmosphere;
1-(bromomethyl)-4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)benzene;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1016/j.tetlet.2014.02.047
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1585235-84-2
15-(4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl)-1,1,1-triphenyl-2,5,8,11,14-pentaoxapentadecane
- Guidance literature:
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Multi-step reaction with 3 steps
1.1: tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate / 1,2-dimethoxyethane; water / 24 h / 90 °C / Inert atmosphere
2.1: phosphorus tribromide / dichloromethane / 2 h / 0 - 20 °C
3.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 20 °C / Inert atmosphere
3.2: 12 h / 20 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); phosphorus tribromide; sodium hydride; sodium hydrogencarbonate;
In
tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; water; mineral oil;
1.1: |Suzuki Coupling;
DOI:10.1016/j.tetlet.2014.02.047
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1585235-84-2
15-(4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl)-1,1,1-triphenyl-2,5,8,11,14-pentaoxapentadecane
- Guidance literature:
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Multi-step reaction with 5 steps
1.1: chloro-trimethyl-silane; zinc / tetrahydrofuran / 15.15 h / 30 °C / Inert atmosphere
1.2: 12 h / 45 °C / Inert atmosphere
2.1: n-butyllithium; N,N-dimethyl-formamide / tetrahydrofuran / 2.5 h / -40 °C / Inert atmosphere
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C
4.1: phosphorus tribromide / dichloromethane / 2 h / 0 - 20 °C
5.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 20 °C / Inert atmosphere
5.2: 12 h / 20 °C / Inert atmosphere
With
lithium aluminium tetrahydride; n-butyllithium; chloro-trimethyl-silane; phosphorus tribromide; sodium hydride; N,N-dimethyl-formamide; zinc;
In
tetrahydrofuran; dichloromethane; mineral oil;
DOI:10.1016/j.tetlet.2014.02.047
