2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol

Base Information

• Chemical Name: 2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol
• CAS No.: 571177-12-3
• Molecular Formula: C₂₆H₃₇N₃O₄Si
• Molecular Weight: 483.683

Synonyms:2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol

Chemical Property of 2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol

There total 2 articles about 2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

tert-butyldimethylsilyl chloride (18162-48-6) + 2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-D-glucitol (171973-88-9) → 2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol (571177-12-3)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 15h;

DOI:10.1016/S0040-4020(03)00257-6

Reference yield:

1,2:5,6-Dianhydro-3,4-di-O-benzyl-D-mannitol (157363-85-4) → 2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol (571177-12-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / NaN₃; silica gel / acetonitrile / 48 h / Heating

2: 95 percent / imidazole / dimethylformamide / 15 h / 20 °C

With 1H-imidazole; sodium azide; silica gel; In N,N-dimethyl-formamide; acetonitrile;

DOI:10.1016/S0040-4020(03)00257-6

Reference yield: 95.0%

2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol (571177-12-3) → 6-amino-2,5-anhydro-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol (339989-77-4)

Guidance literature:

With hydrogen; palladium; In ethyl acetate; at 20 ℃; for 1h; under 760 Torr;

DOI:10.1016/S0040-4020(03)00257-6

upstream raw materials:

tert-butyldimethylsilyl chloride

2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-D-glucitol

1,2:5,6-Dianhydro-3,4-di-O-benzyl-D-mannitol

Downstream raw materials:

6-amino-2,5-anhydro-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol

N-[6'-(2',5'-anhydro-3',4'-di-O-benzyl-6'-deoxy-D-glucitol)]-3,4-di-O-benzyl-1,5-dideoxy-1,5-imino-L-gulitol

N-[6'-(2',5'-anhydro-3',4'-di-O-benzyl-6'-deoxy-1'-O-tert-butyldimethylsilyl-D-glucitol)]-3,4-di-O-benzyl-1,5-dideoxy-1,5-imino-L-gulitol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 571177-12-3 2,5-anhydro-6-azido-3,4-di-O-benzyl-6-deoxy-1-O-tert-butyldimethylsilyl-D-glucitol

Send

Send

Metric Ton KG G Pound L ML

Send

Send