3,4-Diphenyl-4-{[1-phenyl-meth-(E)-ylidene]-amino}-butyric acid ethyl ester

Base Information

• Chemical Name: 3,4-Diphenyl-4-{[1-phenyl-meth-(E)-ylidene]-amino}-butyric acid ethyl ester
• CAS No.: 227026-28-0
• Molecular Formula: C₂₅H₂₅NO₂
• Molecular Weight: 371.479
• Mol file: 227026-28-0.mol

Synonyms:3,4-Diphenyl-4-{[1-phenyl-meth-(E)-ylidene]-amino}-butyric acid ethyl ester

Chemical Property of 3,4-Diphenyl-4-{[1-phenyl-meth-(E)-ylidene]-amino}-butyric acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 3,4-Diphenyl-4-{[1-phenyl-meth-(E)-ylidene]-amino}-butyric acid ethyl ester

There total 1 articles about 3,4-Diphenyl-4-{[1-phenyl-meth-(E)-ylidene]-amino}-butyric acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

ethyl 3-phenyl-2-propenoate (103-36-6) + N-benzylidene benzylamine (780-25-6) → 3,4-Diphenyl-4-{[1-phenyl-meth-(E)-ylidene]-amino}-butyric acid ethyl ester (227026-28-0)

Guidance literature:

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In water; acetonitrile; at 0 ℃; for 1h;

DOI:10.1080/00304949909355722

Reference yield: 91.0%

3,4-Diphenyl-4-{[1-phenyl-meth-(E)-ylidene]-amino}-butyric acid ethyl ester (227026-28-0) → 4-Amino-3,4-diphenyl-butyric acid ethyl ester; hydrochloride

Guidance literature:

With hydrogenchloride; water; In diethyl ether; at 20 ℃; for 10h;

DOI:10.1080/00304949909355722

Reference yield:

3,4-Diphenyl-4-{[1-phenyl-meth-(E)-ylidene]-amino}-butyric acid ethyl ester (227026-28-0) → β,γ-diphenyl-γ-aminobutyric acid hydrochloride (126491-58-5)

Guidance literature:

With hydrogenchloride; In benzene; for 3h; Yield given; Heating;

upstream raw materials:

ethyl 3-phenyl-2-propenoate

N-benzylidene benzylamine

Downstream raw materials:

β,γ-diphenyl-γ-aminobutyric acid hydrochloride

4,5-diphenyl-2-pyrrolidone