4,5-diphenyl-2-pyrrolidone

Base Information

• Chemical Name: 4,5-diphenyl-2-pyrrolidone
• CAS No.: 109761-20-8
• Molecular Formula: C₁₆H₁₅NO
• Molecular Weight: 237.301
• Mol file: 109761-20-8.mol

Synonyms:

Chemical Property of 4,5-diphenyl-2-pyrrolidone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5-diphenyl-2-pyrrolidone

There total 9 articles about 4,5-diphenyl-2-pyrrolidone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-N-benzylcinnamamide (57152-94-0,104047-17-8,5100-00-5) → 4,5-diphenyl-2-pyrrolidone (109761-20-8)

Guidance literature:

at 950 - 1000 ℃; under 0.0015 Torr;

DOI:10.1016/j.tetlet.2005.03.004

Reference yield:

(E)-3-phenylacrylic acid (140-10-3) → 4,5-diphenyl-2-pyrrolidone (109761-20-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 88 percent / thionyl chloride, pyridine / benzene / 1 h / Heating

2: 92 percent / pyridine / CHCl₃ / 24 h

3: triethylbenzylammonium chloride (TEBAC), 50percent aq. NaOH / acetonitrile / 1 h / Ambient temperature

4: conc. aq. HCl / benzene / 3 h / Heating

5: 71 percent / sodium bicarbonate / benzene; H₂O / 5 h / Heating

With pyridine; hydrogenchloride; sodium hydroxide; thionyl chloride; N-benzyl-N,N,N-triethylammonium chloride; sodium hydrogencarbonate; In chloroform; water; acetonitrile; benzene;

Reference yield:

cinnamic acid menthyl ester (5033-95-4,16205-99-5,72580-35-9,73285-58-2,94440-51-4,141507-28-0) → 4,5-diphenyl-2-pyrrolidone (109761-20-8)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylbenzylammonium chloride (TEBAC), 50percent aq. NaOH / acetonitrile / 1 h / Ambient temperature

2: conc. aq. HCl / benzene / 3 h / Heating

3: 71 percent / sodium bicarbonate / benzene; H₂O / 5 h / Heating

With hydrogenchloride; sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; sodium hydrogencarbonate; In water; acetonitrile; benzene;

upstream raw materials:

(E)-N-benzylcinnamamide

(E)-3-phenylacrylic acid

cinnamic acid menthyl ester

3,4-Diphenyl-4-{[1-phenyl-meth-(E)-ylidene]-amino}-butyric acid ethyl ester