2-(6-allyloxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester

Base Information

• Chemical Name: 2-(6-allyloxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester
• CAS No.: 1556064-29-9
• Molecular Formula: C₂₄H₁₈O₅
• Molecular Weight: 386.404
• Mol file: 1556064-29-9.mol

Synonyms:2-(6-allyloxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester

Chemical Property of 2-(6-allyloxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(6-allyloxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester

There total 2 articles about 2-(6-allyloxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.5%

methyl 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoate (70672-06-9) + allyl bromide (106-95-6) → 2-(6-allyloxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester (1556064-29-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1039/c3ob42326c

Reference yield:

fluorescein free acid (518-45-6) → 2-(6-allyloxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester (1556064-29-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / 12 h / 85 °C

2: potassium carbonate / N,N-dimethyl-formamide / 24 h / 20 °C

With sulfuric acid; potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1039/c3ob42326c

Reference yield:

2-(6-allyloxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester (1556064-29-9) → C24H20O5 (1579977-55-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; for 2.5h;

DOI:10.1039/c3ob42326c

upstream raw materials:

methyl 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoate

allyl bromide

fluorescein free acid

Downstream raw materials:

C₂₄H₂₀O₅

methyl 2-(3-(allyloxy)-6-(3-((tert-butoxycarbonyl)amino)propoxy)-9H-xanthen-9-yl)benzoate

methyl 2-(3-(allyloxy)-6-(3-aminopropoxy)-9H-xanthen-9-yl)benzoate