2-(4-(2-(6-aminopyridin-3-yl)-9-oxopyrido [3,2-c][1,5]naphthyridin-10(9H)-yl)phenyl)-2-methylpropanenitrile

Base Information

Chemical Name:2-(4-(2-(6-aminopyridin-3-yl)-9-oxopyrido [3,2-c][1,5]naphthyridin-10(9H)-yl)phenyl)-2-methylpropanenitrile
CAS No.:1415999-84-6
Molecular Formula:C₂₆H₂₀N₆O
Molecular Weight:432.484
Hs Code.:

Synonyms:2-(4-(2-(6-aminopyridin-3-yl)-9-oxopyrido [3,2-c][1,5]naphthyridin-10(9H)-yl)phenyl)-2-methylpropanenitrile

Suppliers and Price of 2-(4-(2-(6-aminopyridin-3-yl)-9-oxopyrido [3,2-c][1,5]naphthyridin-10(9H)-yl)phenyl)-2-methylpropanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(4-(2-(6-aminopyridin-3-yl)-9-oxopyrido [3,2-c][1,5]naphthyridin-10(9H)-yl)phenyl)-2-methylpropanenitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(4-(2-(6-aminopyridin-3-yl)-9-oxopyrido [3,2-c][1,5]naphthyridin-10(9H)-yl)phenyl)-2-methylpropanenitrile

There total 9 articles about 2-(4-(2-(6-aminopyridin-3-yl)-9-oxopyrido [3,2-c][1,5]naphthyridin-10(9H)-yl)phenyl)-2-methylpropanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.2%

: 14221-01-3
tetrakis(triphenylphosphine) palladium⁽⁰⁾

: 1415999-84-6
2-(4-(2-(6-aminopyridin-3-yl)-9-oxopyrido [3,2-c][1,5]naphthyridin-10(9H)-yl)phenyl)-2-methylpropanenitrile

Guidance literature:: With sodium carbonate; In dichloromethane;

Reference yield: 13.2%

: 827614-64-2
2-aminopyridine-5-boronic acid pinacol ester

: 1416000-76-4
2-(4-(2-chloro-9-oxopyrido[3,2-c][1,5]naphthyridin-10(9H)-yl)phenyl)-2-methyl propanenitrile

: 1415999-84-6
2-(4-(2-(6-aminopyridin-3-yl)-9-oxopyrido [3,2-c][1,5]naphthyridin-10(9H)-yl)phenyl)-2-methylpropanenitrile

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; toluene; for 8h; Inert atmosphere; Reflux;

Reference yield:

: 4487-59-6
2-bromo-5-nitropyridine

: 1415999-84-6
2-(4-(2-(6-aminopyridin-3-yl)-9-oxopyrido [3,2-c][1,5]naphthyridin-10(9H)-yl)phenyl)-2-methylpropanenitrile

Guidance literature:: Multi-step reaction with 9 steps

1: iron; hydrogenchloride / ethanol; water / 5 h / Reflux

2: ethanol / 5 h / Reflux

3: diphenylether / 0.75 h / Reflux

4: dimethyl amine; trichlorophosphate / 3 h / Reflux

5: 1,4-dioxane / 4 h / Reflux

6: sodium tetrahydroborate; ethanol / 24 h / 20 °C

7: manganese(IV) oxide / dichloromethane / 30 h / 20 °C

8: N,N-dimethyl acetamide / 1 h / 160 °C / Microwave irradiation

9: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / ethanol; toluene / 8 h / Inert atmosphere; Reflux

With hydrogenchloride; manganese(IV) oxide; sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; ethanol; iron; sodium carbonate; dimethyl amine; trichlorophosphate; In 1,4-dioxane; diphenylether; ethanol; dichloromethane; N,N-dimethyl acetamide; water; toluene;