Tomoxiprole

Base Information

Chemical Name:Tomoxiprole
CAS No.:76145-76-1
Molecular Formula:C21H20 N2 O
Molecular Weight:316.43
Hs Code.:2933990090
UNII:EZ948T2878
DSSTox Substance ID:DTXSID201032783
Nikkaji Number:J22.778A
Wikidata:Q27277446
NCI Thesaurus Code:C66611
ChEMBL ID:CHEMBL347043
Mol file:76145-76-1.mol

Synonyms:3-(1-methylethyl)-2-(4-methoxyphenyl)-3H-naphth(1,2-d)imidazole;MDL 035;MDL-035;tomoxiprole

Suppliers and Price of Tomoxiprole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TOMOXIPROLE 95.00%
5MG
$ 502.94

Total 13 raw suppliers

Chemical Property of Tomoxiprole

Chemical Property:

Vapor Pressure:2.8E-11mmHg at 25°C
Melting Point:160.5°C
Refractive Index:1.6500 (estimate)
Boiling Point:529.1°C at 760 mmHg
Flash Point:186.5°C
PSA：27.05000
Density:1.178g/cm³
LogP:5.44600
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:316.157563266
Heavy Atom Count:24
Complexity:418

Purity/Quality:

99% ^*data from raw suppliers

TOMOXIPROLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)N1C2=C(C3=CC=CC=C3C=C2)N=C1C4=CC=C(C=C4)OC

Technology Process of Tomoxiprole

There total 5 articles about Tomoxiprole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76145-77-2
Isopropyl-(1-nitroso-naphthalen-2-yl)-amine

: 76145-76-1
3-(1-methylethyl)-2-(4-methoxyphenyl)-3H-naphth<1,2-d>imidazole

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / 5percent Pd/C / toluene / 3 h / 760 Torr / Ambient temperature

2: toluene / 3 h / Heating

3: 5percent Pd/C / toluene / 3.5 h / Heating

With hydrogen; palladium on activated charcoal; In toluene;
DOI:10.1021/jm00371a010

Reference yield:

: 131-91-9
1-Nitroso-2-naphthol

: 76145-76-1
3-(1-methylethyl)-2-(4-methoxyphenyl)-3H-naphth<1,2-d>imidazole

Guidance literature:: Multi-step reaction with 4 steps

1: 69 percent / H₂O / 1 h / 50 °C

2: H₂ / 5percent Pd/C / toluene / 3 h / 760 Torr / Ambient temperature

3: toluene / 3 h / Heating

4: 5percent Pd/C / toluene / 3.5 h / Heating

With hydrogen; palladium on activated charcoal; In water; toluene;
DOI:10.1021/jm00371a010