N-((1R,2R)-2-amino-1,2-diphenylethyl)-4-(trifluoromethoxy)benzenesulfonamide

Base Information

• Chemical Name: N-((1R,2R)-2-amino-1,2-diphenylethyl)-4-(trifluoromethoxy)benzenesulfonamide
• CAS No.: 1394152-29-4
• Molecular Formula: C₂₁H₁₉F₃N₂O₃S
• Molecular Weight: 436.455

Synonyms:N-((1R,2R)-2-amino-1,2-diphenylethyl)-4-(trifluoromethoxy)benzenesulfonamide

Chemical Property of N-((1R,2R)-2-amino-1,2-diphenylethyl)-4-(trifluoromethoxy)benzenesulfonamide

Chemical Property:

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Technology Process of N-((1R,2R)-2-amino-1,2-diphenylethyl)-4-(trifluoromethoxy)benzenesulfonamide

There total 1 articles about N-((1R,2R)-2-amino-1,2-diphenylethyl)-4-(trifluoromethoxy)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R,R)-1,2-diphenylethylenediamine (35132-20-8) + 4-(trifluoro-methoxy)benzene-1-sulfonyl chloride (94108-56-2) → N-((1R,2R)-2-amino-1,2-diphenylethyl)-4-(trifluoromethoxy)benzenesulfonamide (1394152-29-4)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ol301903c

Reference yield:

[Ir(III)(η5-pentamethylcyclopentadienyl)(H2O)3](SO4) (254734-81-1) + N-((1R,2R)-2-amino-1,2-diphenylethyl)-4-(trifluoromethoxy)benzenesulfonamide (1394152-29-4) → C31H36F3IrN2O4S(2+)*O4S(2-) (1394151-92-8)

Guidance literature:

In methanol; water; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ol301903c

upstream raw materials:

(R,R)-1,2-diphenylethylenediamine

4-(trifluoro-methoxy)benzene-1-sulfonyl chloride

Downstream raw materials:

C₃₁H₃₆F₃IrN₂O₄S⁽²⁺⁾*O₄S^(2-)

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