5-acetamido-2-O-benzyl-3,5-dideoxy-D-glycero-D-galacto-2-noneno-1,4-lactone

Base Information

• Chemical Name: 5-acetamido-2-O-benzyl-3,5-dideoxy-D-glycero-D-galacto-2-noneno-1,4-lactone
• CAS No.: 115400-37-8
• Molecular Formula: C₁₈H₂₃NO₈
• Molecular Weight: 381.383
• Mol file: 115400-37-8.mol

Synonyms:5-acetamido-2-O-benzyl-3,5-dideoxy-D-glycero-D-galacto-2-noneno-1,4-lactone

Chemical Property of 5-acetamido-2-O-benzyl-3,5-dideoxy-D-glycero-D-galacto-2-noneno-1,4-lactone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-acetamido-2-O-benzyl-3,5-dideoxy-D-glycero-D-galacto-2-noneno-1,4-lactone

There total 3 articles about 5-acetamido-2-O-benzyl-3,5-dideoxy-D-glycero-D-galacto-2-noneno-1,4-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5-acetamido-3,5-dideoxy-D-glycero-β-D-galacto-2-nonulosonic acid benzyl ester (113757-75-8) → 5-acetamido-2-O-benzyl-3,5-dideoxy-D-glycero-D-galacto-2-noneno-1,4-lactone (115400-37-8)

Guidance literature:

With benzyl bromide; caesium carbonate; In N,N-dimethyl-formamide; at 40 ℃; for 2h;

DOI:10.1248/cpb.35.3609

Reference yield: 78.0%

benzyl bromide (100-39-0) + 5-acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulopyranosylonic acid (99396-00-6) → 5-acetamido-2-O-benzyl-3,5-dideoxy-D-glycero-D-galacto-2-noneno-1,4-lactone (115400-37-8)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 40 ℃; for 2h;

DOI:10.1248/cpb.35.3609

Reference yield:

5-acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulopyranosylonic acid (99396-00-6) → 5-acetamido-2-O-benzyl-3,5-dideoxy-D-glycero-D-galacto-2-noneno-1,4-lactone (115400-37-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / cesium carbonate (Cs₂CO₃) / H₂O; dimethylformamide / 2 h / Ambient temperature

2: 80 percent / cesium carbonate (Cs₂CO₃), benzyl bromide / dimethylformamide / 2 h / 40 °C

With benzyl bromide; caesium carbonate; In water; N,N-dimethyl-formamide;

DOI:10.1248/cpb.35.3609

upstream raw materials:

benzyl bromide

5-acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulopyranosylonic acid

5-acetamido-3,5-dideoxy-D-glycero-β-D-galacto-2-nonulosonic acid benzyl ester