1,1-Diphenylgermacyclopentane

Base Information

• Chemical Name: 1,1-Diphenylgermacyclopentane
• CAS No.: 4514-06-1
• Molecular Formula: C₁₆H₁₈Ge
• Molecular Weight: 282.909
• Mol file: 4514-06-1.mol

Synonyms:1,1-diphenylgermanocyclopentane

Chemical Property of 1,1-Diphenylgermacyclopentane

Chemical Property:

• Vapor Pressure: 0.000156mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1-Diphenylgermacyclopentane

There total 5 articles about 1,1-Diphenylgermacyclopentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

1,4-dibromo-butane (110-52-1) + dichlorodiphenylgermane (1613-66-7) → 1,1-diphenylgermanocyclopentane (4514-06-1)

Guidance literature:

1,4-dibromo-butane; With magnesium; In diethyl ether; at 20 ℃; for 4.5h; Reflux;

dichlorodiphenylgermane; In diethyl ether; for 3h; Reflux;

DOI:10.1039/d0cc00959h

Reference yield: 23.6%

1,4-dibromo-butane (110-52-1) + diphenylgermylenedipotassium (100184-59-6) → diphenylgermane (1675-58-7) + 1,1-diphenylgermanocyclopentane (4514-06-1)

Guidance literature:

With water; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; soln. of Ph2GeK2 in HMPA/THF added to Br(CH2)4Br, stirred at room temp.for 30 min, cooled with water bath, hydrolyzed; extd. with ether, org. layer dried over anhyd. Na2SO4, isolated by preparative GLC and TLC;

DOI:10.1246/bcsj.58.1443

Reference yield: 23.6%

1,4-dibromo-butane (110-52-1) + (diphenylgermylene)dipotassium → 1,1-diphenylgermanocyclopentane (4514-06-1)

Guidance literature:

In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; for 0.5h; Product distribution; Ambient temperature;

DOI:10.1246/bcsj.58.1443

upstream raw materials:

1,4-dibromo-butane

1,1-dichlorogermacyclopentane

diphenylgermylenedipotassium

dichlorodiphenylgermane

Refernces

• 1、 Ninomiya, Ryo,Arai, Kenta,Chen, Gong,Morisaki, Kazuhiro,Kawabata, Takeo,Ueda, Yoshihiro. "?-Silicon-effect-promoted intermolecular site-selective C(sp3)-H amination with dirhodium nitrenes". supporting information. p. 5759 - 5762. Retrieved 2020/06/03.
• 2、 Mochida, Kunio,Matsushige, Naoki,Hamashima, Mari. "Preparation and Some Reactions of Diarylgermylenedialkali Metals". . p. 1443 - 1447. Retrieved 2007/10/02.